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Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
Tang AT, Sullivan KR, Hong CC, Goddard LM, Mahadevan A, Ren A, Pardo H, Peiper A, Griffin E, Tanes C, Mattei LM, Yang J, Li L, Mericko-Ishizuka P, Shen L, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Rödel CJ, Li N, Zhu Q, Whitehead KJ, Zheng X, Akers A, Morrison L, Kim H, Bittinger K, Lengner CJ, Schwaninger M, Velcich A, Augenlicht L, Abdelilah-Seyfried S, Min W, Marchuk DA, Awad IA, Kahn ML. Tang AT, et al. Sci Transl Med. 2019 Nov 27;11(520):eaaw3521. doi: 10.1126/scitranslmed.aaw3521. Sci Transl Med. 2019. PMID: 31776290 Free PMC article.
Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.
Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, Faurobert E, von Kries JP, Campillos M, Tournier-Lasserve E, Derry WB, Abdelilah-Seyfried S. Otten C, et al. EMBO Mol Med. 2018 Oct;10(10):e9155. doi: 10.15252/emmm.201809155. EMBO Mol Med. 2018. PMID: 30181117 Free PMC article.
Novel Chronic Mouse Model of Cerebral Cavernous Malformations.
Cardoso C, Arnould M, De Luca C, Otten C, Abdelilah-Seyfried S, Heredia A, Leutenegger AL, Schwaninger M, Tournier-Lasserve E, Boulday G. Cardoso C, et al. Stroke. 2020 Apr;51(4):1272-1278. doi: 10.1161/STROKEAHA.119.027207. Epub 2020 Jan 29. Stroke. 2020. PMID: 31992178
Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations.
Pham VC, Rödel CJ, Valentino M, Malinverno M, Paolini A, Münch J, Pasquier C, Onyeogaziri FC, Lazovic B, Girard R, Koskimäki J, Hußmann M, Keith B, Jachimowicz D, Kohl F, Hagelkruys A, Penninger JM, Schulte-Merker S, Awad IA, Hicks R, Magnusson PU, Faurobert E, Pagani M, Abdelilah-Seyfried S. Pham VC, et al. Among authors: abdelilah seyfried s. EMBO Mol Med. 2024 Nov;16(11):2827-2855. doi: 10.1038/s44321-024-00152-9. Epub 2024 Oct 14. EMBO Mol Med. 2024. PMID: 39402138 Free PMC article.
Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteins.
Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupé S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S. Renz M, et al. Dev Cell. 2015 Jan 26;32(2):181-90. doi: 10.1016/j.devcel.2014.12.016. Dev Cell. 2015. PMID: 25625207 Free article.
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