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Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity.
Santoro AM, Lanza V, Bellia F, Sbardella D, Tundo GR, Cannizzo A, Grasso G, Arizzi M, Nicoletti VG, Alcaro S, Costa G, Pietropaolo A, Malgieri G, D'Abrosca G, Fattorusso R, García-Viñuales S, Ahmed IMM, Coletta M, Milardi D. Santoro AM, et al. Among authors: fattorusso r. ChemMedChem. 2020 Feb 5;15(3):302-316. doi: 10.1002/cmdc.201900612. Epub 2019 Dec 17. ChemMedChem. 2020. PMID: 31797568
The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain.
Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R. Malgieri G, et al. Among authors: fattorusso r. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17341-6. doi: 10.1073/pnas.0706659104. Epub 2007 Oct 23. Proc Natl Acad Sci U S A. 2007. PMID: 17956987 Free PMC article.
The structural role of the zinc ion can be dispensable in prokaryotic zinc-finger domains.
Baglivo I, Russo L, Esposito S, Malgieri G, Renda M, Salluzzo A, Di Blasio B, Isernia C, Fattorusso R, Pedone PV. Baglivo I, et al. Among authors: fattorusso r. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6933-8. doi: 10.1073/pnas.0810003106. Epub 2009 Apr 15. Proc Natl Acad Sci U S A. 2009. PMID: 19369210 Free PMC article.
The inorganic perspective of nerve growth factor: interactions of Cu2+ and Zn2+ with the N-terminus fragment of nerve growth factor encompassing the recognition domain of the TrkA receptor.
Travaglia A, Arena G, Fattorusso R, Isernia C, La Mendola D, Malgieri G, Nicoletti VG, Rizzarelli E. Travaglia A, et al. Among authors: fattorusso r. Chemistry. 2011 Mar 21;17(13):3726-38. doi: 10.1002/chem.201002294. Epub 2011 Feb 25. Chemistry. 2011. PMID: 21394800
121 results