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Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL. Lord SR, et al. Br J Cancer. 2020 Jan;122(2):258-265. doi: 10.1038/s41416-019-0665-5. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819193 Free PMC article. Clinical Trial.
Gene expression and hypoxia in breast cancer.
Favaro E, Lord S, Harris AL, Buffa FM. Favaro E, et al. Genome Med. 2011 Aug 26;3(8):55. doi: 10.1186/gm271. Genome Med. 2011. PMID: 21875443 Free PMC article.
Imaging tumour hypoxia with positron emission tomography.
Fleming IN, Manavaki R, Blower PJ, West C, Williams KJ, Harris AL, Domarkas J, Lord S, Baldry C, Gilbert FJ. Fleming IN, et al. Br J Cancer. 2015 Jan 20;112(2):238-50. doi: 10.1038/bjc.2014.610. Epub 2014 Dec 16. Br J Cancer. 2015. PMID: 25514380 Free PMC article. Review.
Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.
Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, Sharma A, Bidaut L, Pollak M, Roy PG, Karpe F, James T, English R, Adams RF, Campo L, Ayers L, Snell C, Roxanis I, Frezza C, Fenwick JD, Buffa FM, Harris AL. Lord SR, et al. Cell Metab. 2018 Nov 6;28(5):679-688.e4. doi: 10.1016/j.cmet.2018.08.021. Epub 2018 Sep 20. Cell Metab. 2018. PMID: 30244975 Free PMC article. Clinical Trial.
572 results