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HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.
Arasu UT, Deen AJ, Pasonen-Seppänen S, Heikkinen S, Lalowski M, Kärnä R, Härkönen K, Mäkinen P, Lázaro-Ibáñez E, Siljander PR, Oikari S, Levonen AL, Rilla K. Arasu UT, et al. Among authors: oikari s. Cell Mol Life Sci. 2020 Oct;77(20):4093-4115. doi: 10.1007/s00018-019-03399-5. Epub 2019 Dec 9. Cell Mol Life Sci. 2020. PMID: 31820036 Free PMC article.
Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.
Jokela TA, Makkonen KM, Oikari S, Kärnä R, Koli E, Hart GW, Tammi RH, Carlberg C, Tammi MI. Jokela TA, et al. Among authors: oikari s. J Biol Chem. 2011 Sep 23;286(38):33632-40. doi: 10.1074/jbc.M111.265637. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795679 Free PMC article.
Hyaluronan production enhances shedding of plasma membrane-derived microvesicles.
Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VVT, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI. Rilla K, et al. Among authors: oikari s. Exp Cell Res. 2013 Aug 1;319(13):2006-2018. doi: 10.1016/j.yexcr.2013.05.021. Epub 2013 Jun 1. Exp Cell Res. 2013. PMID: 23732660
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression.
Deen AJ, Arasu UT, Pasonen-Seppänen S, Hassinen A, Takabe P, Wojciechowski S, Kärnä R, Rilla K, Kellokumpu S, Tammi R, Tammi M, Oikari S. Deen AJ, et al. Among authors: oikari s. Cell Mol Life Sci. 2016 Aug;73(16):3183-204. doi: 10.1007/s00018-016-2158-5. Epub 2016 Feb 16. Cell Mol Life Sci. 2016. PMID: 26883802 Free PMC article.
44 results