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199 results

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Page 1
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y. Chen S, et al. Among authors: link dc. Nat Commun. 2019 Dec 11;10(1):5649. doi: 10.1038/s41467-019-13542-2. Nat Commun. 2019. PMID: 31827082 Free PMC article.
Age-related mutations associated with clonal hematopoietic expansion and malignancies.
Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC, McMichael JF, Schmidt HK, Yellapantula V, Miller CA, Ozenberger BA, Welch JS, Link DC, Walter MJ, Mardis ER, Dipersio JF, Chen F, Wilson RK, Ley TJ, Ding L. Xie M, et al. Among authors: link dc. Nat Med. 2014 Dec;20(12):1472-8. doi: 10.1038/nm.3733. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326804 Free PMC article.
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Graubert TA, Ley TJ, Druley T, Link DC, Wilson RK. Wong TN, et al. Among authors: link dc. Nature. 2015 Feb 26;518(7540):552-555. doi: 10.1038/nature13968. Epub 2014 Dec 8. Nature. 2015. PMID: 25487151 Free PMC article.
Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.
Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, Wilson RK, Ley TJ, Link DC. Wong TN, et al. Among authors: link dc. Blood. 2016 Feb 18;127(7):893-7. doi: 10.1182/blood-2015-10-677021. Epub 2015 Dec 2. Blood. 2016. PMID: 26631115 Free PMC article.
'CHIP'ping away at clonal hematopoiesis.
Link DC, Walter MJ. Link DC, et al. Leukemia. 2016 Aug;30(8):1633-5. doi: 10.1038/leu.2016.130. Epub 2016 Jun 17. Leukemia. 2016. PMID: 27311932 No abstract available.
miR-125b promotes leukemogenesis via VEGFA.
Wong TN, Link DC. Wong TN, et al. Among authors: link dc. Blood. 2017 Mar 16;129(11):1409-1410. doi: 10.1182/blood-2017-01-761544. Blood. 2017. PMID: 28302689 Free article. No abstract available.
Somatic mutations and clonal hematopoiesis in congenital neutropenia.
Xia J, Miller CA, Baty J, Ramesh A, Jotte MRM, Fulton RS, Vogel TP, Cooper MA, Walkovich KJ, Makaryan V, Bolyard AA, Dinauer MC, Wilson DB, Vlachos A, Myers KC, Rothbaum RJ, Bertuch AA, Dale DC, Shimamura A, Boxer LA, Link DC. Xia J, et al. Among authors: link dc. Blood. 2018 Jan 25;131(4):408-416. doi: 10.1182/blood-2017-08-801985. Epub 2017 Nov 1. Blood. 2018. PMID: 29092827 Free PMC article.
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.
Wong TN, Miller CA, Jotte MRM, Bagegni N, Baty JD, Schmidt AP, Cashen AF, Duncavage EJ, Helton NM, Fiala M, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, Vij R, DiPersio JF, Welch JS, Graubert TA, Walter MJ, Ley TJ, Link DC. Wong TN, et al. Among authors: link dc. Nat Commun. 2018 Jan 31;9(1):455. doi: 10.1038/s41467-018-02858-0. Nat Commun. 2018. PMID: 29386642 Free PMC article.
199 results