Ward N - Search Results

1

Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations.

Ji C, Li Y, Kittredge A, Hopiavuori A, Ward N, Yao P, Fukuda Y, Zhang Y, Tsang SH, Yang T. Ji C, et al. Among authors: ward n. Sci Rep. 2019 Dec 13;9(1):19026. doi: 10.1038/s41598-019-54892-7. Sci Rep. 2019. PMID: 31836750 Free PMC article.

2

Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca²⁺-dependent Cl^- currents in human RPE.

Li Y, Zhang Y, Xu Y, Kittredge A, Ward N, Chen S, Tsang SH, Yang T. Li Y, et al. Among authors: ward n. Elife. 2017 Oct 24;6:e29914. doi: 10.7554/eLife.29914. Elife. 2017. PMID: 29063836 Free PMC article.

3

ATP activates bestrophin ion channels through direct interaction.

Zhang Y, Kittredge A, Ward N, Ji C, Chen S, Yang T. Zhang Y, et al. Among authors: ward n. Nat Commun. 2018 Aug 7;9(1):3126. doi: 10.1038/s41467-018-05616-4. Nat Commun. 2018. PMID: 30087350 Free PMC article.

4

Expression and Purification of Mammalian Bestrophin Ion Channels.

Kittredge A, Ward N, Hopiavuori A, Zhang Y, Yang T. Kittredge A, et al. Among authors: ward n. J Vis Exp. 2018 Aug 2;(138):57832. doi: 10.3791/57832. J Vis Exp. 2018. PMID: 30124653 Free PMC article.

5

Dual Ca²⁺-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.

Ji C, Kittredge A, Hopiavuori A, Ward N, Chen S, Fukuda Y, Zhang Y, Yang T. Ji C, et al. Among authors: ward n. Commun Biol. 2019 Jun 24;2:240. doi: 10.1038/s42003-019-0433-3. eCollection 2019. Commun Biol. 2019. PMID: 31263784 Free PMC article.

6

Structural and functional characterization of the bestrophin-2 anion channel.

Owji AP, Zhao Q, Ji C, Kittredge A, Hopiavuori A, Fu Z, Ward N, Clarke OB, Shen Y, Zhang Y, Hendrickson WA, Yang T. Owji AP, et al. Among authors: ward n. Nat Struct Mol Biol. 2020 Apr;27(4):382-391. doi: 10.1038/s41594-020-0402-z. Epub 2020 Apr 6. Nat Struct Mol Biol. 2020. PMID: 32251414 Free PMC article.

7

Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission.

Foley K, Altimimi H, Hou H, Zhang Y, McKee C, Papasergi-Scott MM, Yang H, Mayer A, Ward N, MacLean DM, Nairn AC, Stellwagen D, Xia H. Foley K, et al. Among authors: ward n. Front Synaptic Neurosci. 2022 Oct 6;14:1021832. doi: 10.3389/fnsyn.2022.1021832. eCollection 2022. Front Synaptic Neurosci. 2022. PMID: 36276179 Free PMC article.

8

Regulation of PP1 interaction with I-2, neurabin, and F-actin.

Foley K, Ward N, Hou H, Mayer A, McKee C, Xia H. Foley K, et al. Among authors: ward n. Mol Cell Neurosci. 2023 Mar;124:103796. doi: 10.1016/j.mcn.2022.103796. Epub 2022 Nov 25. Mol Cell Neurosci. 2023. PMID: 36442541 Free PMC article.

9

Nuclear Inhibitor of Protein Phosphatase 1 (NIPP1) Regulates CNS Tau Phosphorylation and Myelination During Development.

McKee C, Shrager P, Mazumder AG, Ganguly A, Mayer A, Foley K, Ward N, Youngman M, Hou H, Xia H. McKee C, et al. Among authors: ward n. Mol Neurobiol. 2022 Dec;59(12):7486-7494. doi: 10.1007/s12035-022-03040-w. Epub 2022 Oct 6. Mol Neurobiol. 2022. PMID: 36198882 Free PMC article.

10

A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer.

Messina MS, Torrente L, Pezacki AT, Humpel HI, Li EL, Miller SG, Verdejo-Torres O, Padilla-Benavides T, Brady DC, Killilea DW, Killilea AN, Ralle M, Ward NP, Ohata J, DeNicola GM, Chang CJ. Messina MS, et al. Among authors: ward np. Proc Natl Acad Sci U S A. 2025 Jan 21;122(3):e2412816122. doi: 10.1073/pnas.2412816122. Epub 2025 Jan 15. Proc Natl Acad Sci U S A. 2025. PMID: 39813247

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