Zhang Y - Search Results

1

Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations.

Ji C, Li Y, Kittredge A, Hopiavuori A, Ward N, Yao P, Fukuda Y, Zhang Y, Tsang SH, Yang T. Ji C, et al. Among authors: zhang y. Sci Rep. 2019 Dec 13;9(1):19026. doi: 10.1038/s41598-019-54892-7. Sci Rep. 2019. PMID: 31836750 Free PMC article.

2

Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca²⁺-dependent Cl^- currents in human RPE.

Li Y, Zhang Y, Xu Y, Kittredge A, Ward N, Chen S, Tsang SH, Yang T. Li Y, et al. Among authors: zhang y. Elife. 2017 Oct 24;6:e29914. doi: 10.7554/eLife.29914. Elife. 2017. PMID: 29063836 Free PMC article.

3

ATP activates bestrophin ion channels through direct interaction.

Zhang Y, Kittredge A, Ward N, Ji C, Chen S, Yang T. Zhang Y, et al. Nat Commun. 2018 Aug 7;9(1):3126. doi: 10.1038/s41467-018-05616-4. Nat Commun. 2018. PMID: 30087350 Free PMC article.

4

Expression and Purification of Mammalian Bestrophin Ion Channels.

Kittredge A, Ward N, Hopiavuori A, Zhang Y, Yang T. Kittredge A, et al. Among authors: zhang y. J Vis Exp. 2018 Aug 2;(138):57832. doi: 10.3791/57832. J Vis Exp. 2018. PMID: 30124653 Free PMC article.

5

Differentiation, Maintenance, and Analysis of Human Retinal Pigment Epithelium Cells: A Disease-in-a-dish Model for BEST1 Mutations.

Kittredge A, Ji C, Zhang Y, Yang T. Kittredge A, et al. Among authors: zhang y. J Vis Exp. 2018 Aug 24;(138):57791. doi: 10.3791/57791. J Vis Exp. 2018. PMID: 30199040 Free PMC article.

6

Dual Ca²⁺-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.

Ji C, Kittredge A, Hopiavuori A, Ward N, Chen S, Fukuda Y, Zhang Y, Yang T. Ji C, et al. Among authors: zhang y. Commun Biol. 2019 Jun 24;2:240. doi: 10.1038/s42003-019-0433-3. eCollection 2019. Commun Biol. 2019. PMID: 31263784 Free PMC article.

7

Structural and functional characterization of the bestrophin-2 anion channel.

Owji AP, Zhao Q, Ji C, Kittredge A, Hopiavuori A, Fu Z, Ward N, Clarke OB, Shen Y, Zhang Y, Hendrickson WA, Yang T. Owji AP, et al. Among authors: zhang y. Nat Struct Mol Biol. 2020 Apr;27(4):382-391. doi: 10.1038/s41594-020-0402-z. Epub 2020 Apr 6. Nat Struct Mol Biol. 2020. PMID: 32251414 Free PMC article.

8

Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations.

Zhao Q, Kong Y, Kittredge A, Li Y, Shen Y, Zhang Y, Tsang SH, Yang T. Zhao Q, et al. Among authors: zhang y. Elife. 2021 Jun 1;10:e67622. doi: 10.7554/eLife.67622. Elife. 2021. PMID: 34061021 Free PMC article.

9

Evaluating BEST1 mutations in pluripotent stem cell-derived retinal pigment epithelial cells.

Kittredge A, Zhang Y, Yang T. Kittredge A, et al. Among authors: zhang y. Methods Enzymol. 2021;654:365-382. doi: 10.1016/bs.mie.2021.01.004. Epub 2021 Feb 27. Methods Enzymol. 2021. PMID: 34120722 Free PMC article.

10

Structure and Function of the Bestrophin family of calcium-activated chloride channels.

Owji AP, Kittredge A, Zhang Y, Yang T. Owji AP, et al. Among authors: zhang y. Channels (Austin). 2021 Dec;15(1):604-623. doi: 10.1080/19336950.2021.1981625. Channels (Austin). 2021. PMID: 34612806 Free PMC article. Review.

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