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Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice.
Yang C, Meng Y, Wang X, Li X, Yu T, Liao W, Xie W, Jiang Q, Wang H, Shi C, Jiao W, Bian X, Hu F, Wang X, Liu Y, Zhang L, Wang K, Sun Q. Yang C, et al. Among authors: jiao w. J Med Chem. 2024 Apr 25;67(8):6344-6364. doi: 10.1021/acs.jmedchem.3c02323. Epub 2024 Feb 23. J Med Chem. 2024. PMID: 38393821
Pharmacological characterization of JWX-A0108 as a novel type I positive allosteric modulator of α7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model.
Sun LL, Yang TY, Wei NN, Lu W, Jiao WX, Zhou QQ, Miao YZ, Gao Q, Wang XT, Sun Q, Wang K. Sun LL, et al. Among authors: jiao wx. Acta Pharmacol Sin. 2019 Jun;40(6):737-745. doi: 10.1038/s41401-018-0163-y. Epub 2018 Oct 17. Acta Pharmacol Sin. 2019. PMID: 30333556 Free PMC article.
1,456 results