Nivina A - Search Results

1

Evolution and Diversity of Assembly-Line Polyketide Synthases.

Nivina A, Yuet KP, Hsu J, Khosla C. Nivina A, et al. Chem Rev. 2019 Dec 26;119(24):12524-12547. doi: 10.1021/acs.chemrev.9b00525. Epub 2019 Dec 15. Chem Rev. 2019. PMID: 31838842 Free PMC article. Review.

2

Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains.

Klaus M, D'Souza AD, Nivina A, Khosla C, Grininger M. Klaus M, et al. Among authors: nivina a. ACS Chem Biol. 2019 Mar 15;14(3):426-433. doi: 10.1021/acschembio.8b01060. Epub 2019 Feb 11. ACS Chem Biol. 2019. PMID: 30682239 Free PMC article.

3

GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification.

Nivina A, Herrera Paredes S, Fraser HB, Khosla C. Nivina A, et al. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2100751118. doi: 10.1073/pnas.2100751118. Proc Natl Acad Sci U S A. 2021. PMID: 34162709 Free PMC article.

4

Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality.

Grieb MS, Nivina A, Cheeseman BL, Hartmann A, Mazel D, Schlierf M. Grieb MS, et al. Among authors: nivina a. Nucleic Acids Res. 2017 Oct 13;45(18):10555-10563. doi: 10.1093/nar/gkx670. Nucleic Acids Res. 2017. PMID: 28985409 Free PMC article.

5

The Integron: Adaptation On Demand.

Escudero JA, Loot C, Nivina A, Mazel D. Escudero JA, et al. Among authors: nivina a. Microbiol Spectr. 2015 Apr;3(2):MDNA3-0019-2014. doi: 10.1128/microbiolspec.MDNA3-0019-2014. Microbiol Spectr. 2015. PMID: 26104695 Free article. Review.

6

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites.

Nivina A, Escudero JA, Vit C, Mazel D, Loot C. Nivina A, et al. Nucleic Acids Res. 2016 Sep 19;44(16):7792-803. doi: 10.1093/nar/gkw646. Epub 2016 Aug 5. Nucleic Acids Res. 2016. PMID: 27496283 Free PMC article.

7

Structural heterogeneity of attC integron recombination sites revealed by optical tweezers.

Mukhortava A, Pöge M, Grieb MS, Nivina A, Loot C, Mazel D, Schlierf M. Mukhortava A, et al. Among authors: nivina a. Nucleic Acids Res. 2019 Feb 28;47(4):1861-1870. doi: 10.1093/nar/gky1258. Nucleic Acids Res. 2019. PMID: 30566629 Free PMC article.

8

Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation.

Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D. Escudero JA, et al. Among authors: nivina a. Nat Commun. 2016 Mar 10;7:10937. doi: 10.1038/ncomms10937. Nat Commun. 2016. PMID: 26961432 Free PMC article.

9

Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation.

Escudero JA, Nivina A, Cambray G, López-Igual R, Loot C, Mazel D. Escudero JA, et al. Among authors: nivina a. Biotechnol Bioeng. 2018 Jan;115(1):184-191. doi: 10.1002/bit.26450. Epub 2017 Oct 16. Biotechnol Bioeng. 2018. PMID: 28898391

10

Structure-specific DNA recombination sites: Design, validation, and machine learning-based refinement.

Nivina A, Grieb MS, Loot C, Bikard D, Cury J, Shehata L, Bernardes J, Mazel D. Nivina A, et al. Sci Adv. 2020 Jul 24;6(30):eaay2922. doi: 10.1126/sciadv.aay2922. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832653 Free PMC article.

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