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ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics.
Liu H, He Z, Germič N, Ademi H, Frangež Ž, Felser A, Peng S, Riether C, Djonov V, Nuoffer JM, Bovet C, Mlinarič-Raščan I, Zlobec I, Fiedler M, Perren A, Simon HU. Liu H, et al. Cell Death Differ. 2020 Jun;27(6):1965-1980. doi: 10.1038/s41418-019-0476-5. Epub 2019 Dec 16. Cell Death Differ. 2020. PMID: 31844253 Free PMC article.
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