Abouzayed A - Search Results

1

Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.

Deyev SM, Vorobyeva A, Schulga A, Abouzayed A, Günther T, Garousi J, Konovalova E, Ding H, Gräslund T, Orlova A, Tolmachev V. Deyev SM, et al. Among authors: abouzayed a. Int J Biol Macromol. 2020 Feb 15;145:216-225. doi: 10.1016/j.ijbiomac.2019.12.147. Epub 2019 Dec 19. Int J Biol Macromol. 2020. PMID: 31863835 Free article.

2

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer.

Abouzayed A, Yim CB, Mitran B, Rinne SS, Tolmachev V, Larhed M, Rosenström U, Orlova A. Abouzayed A, et al. Pharmaceutics. 2019 Jul 23;11(7):358. doi: 10.3390/pharmaceutics11070358. Pharmaceutics. 2019. PMID: 31340483 Free PMC article.

3

Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart.

Oroujeni M, Abouzayed A, Lundmark F, Mitran B, Orlova A, Tolmachev V, Rosenström U. Oroujeni M, et al. Among authors: abouzayed a. Pharmaceutics. 2019 Aug 2;11(8):380. doi: 10.3390/pharmaceutics11080380. Pharmaceutics. 2019. PMID: 31382362 Free PMC article.

4

Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer.

Mitran B, Varasteh Z, Abouzayed A, Rinne SS, Puuvuori E, De Rosa M, Larhed M, Tolmachev V, Orlova A, Rosenström U. Mitran B, et al. Among authors: abouzayed a. Cancers (Basel). 2019 Sep 14;11(9):1371. doi: 10.3390/cancers11091371. Cancers (Basel). 2019. PMID: 31540122 Free PMC article.

5

Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules.

Rinne SS, Dahlsson Leitao C, Gentry J, Mitran B, Abouzayed A, Tolmachev V, Ståhl S, Löfblom J, Orlova A. Rinne SS, et al. Among authors: abouzayed a. Sci Rep. 2019 Nov 27;9(1):17710. doi: 10.1038/s41598-019-54149-3. Sci Rep. 2019. PMID: 31776413 Free PMC article.

6

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model.

Lundmark F, Abouzayed A, Mitran B, Rinne SS, Varasteh Z, Larhed M, Tolmachev V, Rosenström U, Orlova A. Lundmark F, et al. Among authors: abouzayed a. Pharmaceutics. 2020 Jul 1;12(7):614. doi: 10.3390/pharmaceutics12070614. Pharmaceutics. 2020. PMID: 32630176 Free PMC article.

7

Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1.

Vorobyeva A, Bezverkhniaia E, Konovalova E, Schulga A, Garousi J, Vorontsova O, Abouzayed A, Orlova A, Deyev S, Tolmachev V. Vorobyeva A, et al. Among authors: abouzayed a. Molecules. 2020 Oct 14;25(20):4719. doi: 10.3390/molecules25204719. Molecules. 2020. PMID: 33066684 Free PMC article.

8

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer.

Abouzayed A, Tano H, Nagy Á, Rinne SS, Wadeea F, Kumar S, Westerlund K, Tolmachev V, Eriksson Karlström A, Orlova A. Abouzayed A, et al. Pharmaceutics. 2020 Oct 16;12(10):977. doi: 10.3390/pharmaceutics12100977. Pharmaceutics. 2020. PMID: 33081166 Free PMC article.

9

Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches.

Güler R, Svedmark SF, Abouzayed A, Orlova A, Löfblom J. Güler R, et al. Among authors: abouzayed a. Sci Rep. 2020 Oct 23;10(1):18148. doi: 10.1038/s41598-020-74560-5. Sci Rep. 2020. PMID: 33097752 Free PMC article.

10

Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer.

Abouzayed A, Rinne SS, Sabahnoo H, Sörensen J, Chernov V, Tolmachev V, Orlova A. Abouzayed A, et al. Pharmaceutics. 2021 Jan 30;13(2):182. doi: 10.3390/pharmaceutics13020182. Pharmaceutics. 2021. PMID: 33573232 Free PMC article.

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