Ding H - Search Results

1

Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.

Deyev SM, Vorobyeva A, Schulga A, Abouzayed A, Günther T, Garousi J, Konovalova E, Ding H, Gräslund T, Orlova A, Tolmachev V. Deyev SM, et al. Among authors: ding h. Int J Biol Macromol. 2020 Feb 15;145:216-225. doi: 10.1016/j.ijbiomac.2019.12.147. Epub 2019 Dec 19. Int J Biol Macromol. 2020. PMID: 31863835 Free article.

2

Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors.

Altai M, Liu H, Ding H, Mitran B, Edqvist PH, Tolmachev V, Orlova A, Gräslund T. Altai M, et al. Among authors: ding h. J Control Release. 2018 Oct 28;288:84-95. doi: 10.1016/j.jconrel.2018.08.040. Epub 2018 Aug 30. J Control Release. 2018. PMID: 30172673

3

Potent and specific fusion toxins consisting of a HER2‑binding, ABD‑derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A.

Liu H, Lindbo S, Ding H, Altai M, Garousi J, Orlova A, Tolmachev V, Hober S, Gräslund T. Liu H, et al. Among authors: ding h. Int J Oncol. 2019 Jul;55(1):309-319. doi: 10.3892/ijo.2019.4814. Epub 2019 May 28. Int J Oncol. 2019. PMID: 31180549

4

Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates.

Ding H, Altai M, Rinne SS, Vorobyeva A, Tolmachev V, Gräslund T, Orlova A. Ding H, et al. Cancers (Basel). 2019 Aug 14;11(8):1168. doi: 10.3390/cancers11081168. Cancers (Basel). 2019. PMID: 31416167 Free PMC article.

5

HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution.

Ding H, Altai M, Yin W, Lindbo S, Liu H, Garousi J, Xu T, Orlova A, Tolmachev V, Hober S, Gräslund T. Ding H, et al. Pharmaceutics. 2020 Apr 24;12(4):391. doi: 10.3390/pharmaceutics12040391. Pharmaceutics. 2020. PMID: 32344762 Free PMC article.

6

Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model.

Xu T, Ding H, Vorobyeva A, Oroujeni M, Orlova A, Tolmachev V, Gräslund T. Xu T, et al. Among authors: ding h. Cancers (Basel). 2020 Dec 30;13(1):85. doi: 10.3390/cancers13010085. Cancers (Basel). 2020. PMID: 33396753 Free PMC article.

7

Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution.

Ding H, Xu T, Zhang J, Tolmachev V, Oroujeni M, Orlova A, Gräslund T, Vorobyeva A. Ding H, et al. Pharmaceutics. 2021 Mar 23;13(3):430. doi: 10.3390/pharmaceutics13030430. Pharmaceutics. 2021. PMID: 33806887 Free PMC article.

8

Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1.

Deyev SM, Xu T, Liu Y, Schulga A, Konovalova E, Garousi J, Rinne SS, Larkina M, Ding H, Gräslund T, Orlova A, Tolmachev V, Vorobyeva A. Deyev SM, et al. Among authors: ding h. Cancers (Basel). 2021 Jul 17;13(14):3589. doi: 10.3390/cancers13143589. Cancers (Basel). 2021. PMID: 34298801 Free PMC article.

9

Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model.

Xu T, Vorobyeva A, Schulga A, Konovalova E, Vorontsova O, Ding H, Gräslund T, Tashireva LA, Orlova A, Tolmachev V, Deyev SM. Xu T, et al. Among authors: ding h. Cancers (Basel). 2021 Aug 4;13(16):3939. doi: 10.3390/cancers13163939. Cancers (Basel). 2021. PMID: 34439094 Free PMC article.

10

Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein.

Garousi J, Ding H, von Witting E, Xu T, Vorobyeva A, Oroujeni M, Orlova A, Hober S, Gräslund T, Tolmachev V. Garousi J, et al. Among authors: ding h. Pharmaceutics. 2021 Nov 3;13(11):1847. doi: 10.3390/pharmaceutics13111847. Pharmaceutics. 2021. PMID: 34834262 Free PMC article.

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