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Immunity against cancer cells may promote their proliferation and metastasis.
Lin CW, Xie J, Zhang D, Han KH, Grande G, Wu NC, Yang Z, Yea K, Lerner RA. Lin CW, et al. Among authors: zhang d. Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):426-431. doi: 10.1073/pnas.1916833117. Epub 2019 Dec 23. Proc Natl Acad Sci U S A. 2020. PMID: 31871166 Free PMC article.
Switchable targeting of solid tumors by BsCAR T cells.
Stepanov AV, Kalinin RS, Shipunova VO, Zhang D, Xie J, Rubtsov YP, Ukrainskaya VM, Schulga A, Konovalova EV, Volkov DV, Yaroshevich IA, Moysenovich AM, Belogurov AA Jr, Zhang H, Telegin GB, Chernov AS, Maschan MA, Terekhov SS, Wu P, Deyev SM, Lerner RA, Gabibov AG, Altman S. Stepanov AV, et al. Among authors: zhang d, zhang h. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2210562119. doi: 10.1073/pnas.2210562119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343224 Free PMC article.
Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.
Stepanov AV, Xie J, Zhu Q, Shen Z, Su W, Kuai L, Soll R, Rader C, Shaver G, Douthit L, Zhang D, Kalinin R, Fu X, Zhao Y, Qin T, Baran PS, Gabibov AG, Bushnell D, Neri D, Kornberg RD, Lerner RA. Stepanov AV, et al. Among authors: zhang d. Nat Biomed Eng. 2024 May;8(5):529-543. doi: 10.1038/s41551-023-01102-5. Epub 2023 Oct 5. Nat Biomed Eng. 2024. PMID: 37798444
Targeting CD45 by gene-edited CAR T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning.
Stepanova VM, Volkov DV, Osipova DS, Wang W, Hou Y, Pershin DE, Fadeeva MS, Malakhova EA, Kulakovskaya EA, Cuicui L, Mingfeng Z, Zhang H, Xie J, Zhang D, Mamedov IZ, Chernov AS, Telegin GB, Rubtsov YP, Gabibov AG, Wu P, Maschan MA, Stepanov AV. Stepanova VM, et al. Among authors: zhang d, zhang h. Mol Ther Oncol. 2024 Jun 27;32(3):200843. doi: 10.1016/j.omton.2024.200843. eCollection 2024 Sep 19. Mol Ther Oncol. 2024. PMID: 39822756 Free PMC article.
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry.
Kitamura S, Lin TH, Lee CD, Takamura A, Kadam RU, Zhang D, Zhu X, Dada L, Nagai E, Yu W, Yao Y, Sharpless KB, Wilson IA, Wolan DW. Kitamura S, et al. Among authors: zhang d. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2310677121. doi: 10.1073/pnas.2310677121. Epub 2024 May 16. Proc Natl Acad Sci U S A. 2024. PMID: 38753503 Free PMC article.
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