Durrant LG - Search Results

1

Monoclonal Antibody Targeting Sialyl-di-Lewis^a-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential.

Tivadar ST, McIntosh RS, Chua JX, Moss R, Parsons T, Zaitoun AM, Madhusudan S, Durrant LG, Vankemmelbeke M. Tivadar ST, et al. Among authors: durrant lg. Mol Cancer Ther. 2020 Mar;19(3):790-801. doi: 10.1158/1535-7163.MCT-19-0221. Epub 2019 Dec 23. Mol Cancer Ther. 2020. PMID: 31871270

2

Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity.

Chua JX, Vankemmelbeke M, McIntosh RS, Clarke PA, Moss R, Parsons T, Spendlove I, Zaitoun AM, Madhusudan S, Durrant LG. Chua JX, et al. Among authors: durrant lg. Clin Cancer Res. 2015 Jul 1;21(13):2963-74. doi: 10.1158/1078-0432.CCR-14-3030. Epub 2015 Mar 16. Clin Cancer Res. 2015. PMID: 25779947

3

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.

Soliman C, Chua JX, Vankemmelbeke M, McIntosh RS, Guy AJ, Spendlove I, Durrant LG, Ramsland PA. Soliman C, et al. Among authors: durrant lg. J Biol Chem. 2020 Jan 24;295(4):1009-1020. doi: 10.1074/jbc.RA119.011518. Epub 2019 Dec 12. J Biol Chem. 2020. PMID: 31831622 Free PMC article.

4

Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.

Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Among authors: durrant lg. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.

5

Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody.

Soliman C, Guy AJ, Chua JX, Vankemmelbeke M, McIntosh RS, Eastwood S, Truong VK, Elbourne A, Spendlove I, Durrant LG, Ramsland PA. Soliman C, et al. Among authors: durrant lg. Biochem J. 2020 Sep 18;477(17):3219-3235. doi: 10.1042/BCJ20200454. Biochem J. 2020. PMID: 32789497

6

Third-generation antibody drug conjugates for cancer therapy--a balancing act.

Vankemmelbeke M, Durrant L. Vankemmelbeke M, et al. Ther Deliv. 2016;7(3):141-4. doi: 10.4155/tde-2016-0002. Ther Deliv. 2016. PMID: 26893243 No abstract available.

7

A new anticancer glycolipid monoclonal antibody, SC104, which directly induces tumor cell apoptosis.

Durrant LG, Harding SJ, Green NH, Buckberry LD, Parsons T. Durrant LG, et al. Cancer Res. 2006 Jun 1;66(11):5901-9. doi: 10.1158/0008-5472.CAN-05-3812. Cancer Res. 2006. PMID: 16740730

8

Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla.

Storr SJ, Zaitoun AM, Arora A, Durrant LG, Lobo DN, Madhusudan S, Martin SG. Storr SJ, et al. Among authors: durrant lg. BMC Cancer. 2012 Nov 9;12:511. doi: 10.1186/1471-2407-12-511. BMC Cancer. 2012. PMID: 23140395 Free PMC article.

9

Therapeutic targeting of Lewis(y) and Lewis(b) with a novel monoclonal antibody 692/29.

Noble P, Spendlove I, Harding S, Parsons T, Durrant LG. Noble P, et al. Among authors: durrant lg. PLoS One. 2013;8(2):e54892. doi: 10.1371/journal.pone.0054892. Epub 2013 Feb 8. PLoS One. 2013. PMID: 23408949 Free PMC article.

10

Cancer cell associated glycans as targets for immunotherapy.

Vankemmelbeke M, Chua JX, Durrant LG. Vankemmelbeke M, et al. Among authors: durrant lg. Oncoimmunology. 2015 Jul 15;5(1):e1061177. doi: 10.1080/2162402X.2015.1061177. eCollection 2016. Oncoimmunology. 2015. PMID: 26942075 Free PMC article.

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