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Targeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infection.
Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M. Nakagawa S, et al. Among authors: tanaka y. PLoS One. 2013;8(3):e59611. doi: 10.1371/journal.pone.0059611. Epub 2013 Mar 28. PLoS One. 2013. PMID: 23555725 Free PMC article.
Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.
Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T. Tsukuda S, et al. Among authors: tanaka y. J Biol Chem. 2015 Feb 27;290(9):5673-84. doi: 10.1074/jbc.M114.602540. Epub 2014 Dec 30. J Biol Chem. 2015. PMID: 25550158 Free PMC article.
microRNAs and Hepatitis B.
Naito Y, Tanaka Y, Ochiya T. Naito Y, et al. Among authors: tanaka y. Adv Exp Med Biol. 2015;888:389-99. doi: 10.1007/978-3-319-22671-2_19. Adv Exp Med Biol. 2015. PMID: 26663193
A new class of hepatitis B and D virus entry inhibitors, proanthocyanidin and its analogs, that directly act on the viral large surface proteins.
Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Omagari K, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Sureau C, Wakita T. Tsukuda S, et al. Among authors: tanaka y. Hepatology. 2017 Apr;65(4):1104-1116. doi: 10.1002/hep.28952. Epub 2017 Jan 17. Hepatology. 2017. PMID: 27863453
Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment.
Wakasugi H, Takahashi H, Niinuma T, Kitajima H, Oikawa R, Matsumoto N, Takeba Y, Otsubo T, Takagi M, Ariizumi Y, Suzuki M, Okuse C, Iwabuchi S, Nakano M, Akutsu N, Kang JH, Matsui T, Yamada N, Sasaki H, Yamamoto E, Kai M, Sasaki Y, Sasaki S, Tanaka Y, Yotsuyanagi H, Tsutsumi T, Yamamoto H, Tokino T, Nakase H, Suzuki H, Itoh F. Wakasugi H, et al. Among authors: tanaka y. Cancer Lett. 2018 Oct 10;434:91-100. doi: 10.1016/j.canlet.2018.07.019. Epub 2018 Jul 17. Cancer Lett. 2018. PMID: 30026054
Screening of microRNAs for a repressor of hepatitis B virus replication.
Naito Y, Hamada-Tsutsumi S, Yamamoto Y, Kogure A, Yoshioka Y, Watashi K, Ochiya T, Tanaka Y. Naito Y, et al. Among authors: tanaka y. Oncotarget. 2018 Jul 6;9(52):29857-29868. doi: 10.18632/oncotarget.25557. eCollection 2018 Jul 6. Oncotarget. 2018. PMID: 30042818 Free PMC article.
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