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Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells.
Jang BC, Paik JH, Jeong HY, Oh HJ, Park JW, Kwon TK, Song DK, Park JG, Kim SP, Bae JH, Mun KC, Suh MH, Yoshida M, Suh SI. Jang BC, et al. Among authors: kwon tk. Biochem Pharmacol. 2004 Jul 15;68(2):263-74. doi: 10.1016/j.bcp.2004.03.007. Biochem Pharmacol. 2004. PMID: 15193998
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.
Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, Park JW, Choi KS, Kwon TK. Kim YH, et al. Among authors: kwon tk. Free Radic Biol Med. 2008 Mar 15;44(6):1055-68. doi: 10.1016/j.freeradbiomed.2007.12.001. Epub 2007 Dec 8. Free Radic Biol Med. 2008. PMID: 18164688
543 results