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Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies.
Kabanova A, Perez L, Lilleri D, Marcandalli J, Agatic G, Becattini S, Preite S, Fuschillo D, Percivalle E, Sallusto F, Gerna G, Corti D, Lanzavecchia A. Kabanova A, et al. Among authors: perez l. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17965-70. doi: 10.1073/pnas.1415310111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453106 Free PMC article.
Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody.
Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, Ploquin A, Doria-Rose NA, Staupe RP, Bailey M, Shi W, Choe M, Marcus H, Thompson EA, Cagigi A, Silacci C, Fernandez-Rodriguez B, Perez L, Sallusto F, Vanzetta F, Agatic G, Cameroni E, Kisalu N, Gordon I, Ledgerwood JE, Mascola JR, Graham BS, Muyembe-Tamfun JJ, Trefry JC, Lanzavecchia A, Sullivan NJ. Corti D, et al. Among authors: perez l. Science. 2016 Mar 18;351(6279):1339-42. doi: 10.1126/science.aad5224. Epub 2016 Feb 25. Science. 2016. PMID: 26917593
Monoclonal Antibodies to Different Components of the Human Cytomegalovirus (HCMV) Pentamer gH/gL/pUL128L and Trimer gH/gL/gO as well as Antibodies Elicited during Primary HCMV Infection Prevent Epithelial Cell Syncytium Formation.
Gerna G, Percivalle E, Perez L, Lanzavecchia A, Lilleri D. Gerna G, et al. Among authors: perez l. J Virol. 2016 Jun 24;90(14):6216-6223. doi: 10.1128/JVI.00121-16. Print 2016 Jul 15. J Virol. 2016. PMID: 27122579 Free PMC article.
Human cytomegalovirus (HCMV)-specific T cell but not neutralizing or IgG binding antibody responses to glycoprotein complexes gB, gHgLgO, and pUL128L correlate with protection against high HCMV viral load reactivation in solid-organ transplant recipients.
Lilleri D, Zelini P, Fornara C, Zavaglio F, Rampino T, Perez L, Gabanti E, Gerna G. Lilleri D, et al. Among authors: perez l. J Med Virol. 2018 Oct;90(10):1620-1628. doi: 10.1002/jmv.25225. Epub 2018 Jul 10. J Med Virol. 2018. PMID: 29797330
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus.
Marcandalli J, Fiala B, Ols S, Perotti M, de van der Schueren W, Snijder J, Hodge E, Benhaim M, Ravichandran R, Carter L, Sheffler W, Brunner L, Lawrenz M, Dubois P, Lanzavecchia A, Sallusto F, Lee KK, Veesler D, Correnti CE, Stewart LJ, Baker D, Loré K, Perez L, King NP. Marcandalli J, et al. Among authors: perez l. Cell. 2019 Mar 7;176(6):1420-1431.e17. doi: 10.1016/j.cell.2019.01.046. Cell. 2019. PMID: 30849373 Free PMC article.
HCMV Envelope Glycoprotein Diversity Demystified.
Foglierini M, Marcandalli J, Perez L. Foglierini M, et al. Among authors: perez l. Front Microbiol. 2019 May 15;10:1005. doi: 10.3389/fmicb.2019.01005. eCollection 2019. Front Microbiol. 2019. PMID: 31156572 Free PMC article.
2,211 results