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Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
Zheng ZG, Zhang X, Liu XX, Jin XX, Dai L, Cheng HM, Jing D, Thu PM, Zhang M, Li H, Zhu J, Liu C, Xue B, Li Y, Chen L, Peng C, Zhu W, Wang L, Liu J, Li HJ, Li P, Xu X. Zheng ZG, et al. Among authors: cheng hm. Theranostics. 2019 Aug 12;9(20):5769-5783. doi: 10.7150/thno.36505. eCollection 2019. Theranostics. 2019. PMID: 31534518 Free PMC article.
Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway.
Zheng ZG, Zhu ST, Cheng HM, Zhang X, Cheng G, Thu PM, Wang SP, Li HJ, Ding M, Qiang L, Chen XW, Zhong Q, Li P, Xu X. Zheng ZG, et al. Among authors: cheng g, cheng hm. Autophagy. 2021 Jul;17(7):1592-1613. doi: 10.1080/15548627.2020.1757955. Epub 2020 May 20. Autophagy. 2021. PMID: 32432943 Free PMC article.
1,107 results