Ruan M - Search Results

1

Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism.

Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S. Weivoda MM, et al. Among authors: ruan m. Nat Commun. 2020 Jan 7;11(1):87. doi: 10.1038/s41467-019-14003-6. Nat Commun. 2020. PMID: 31911667 Free PMC article. Clinical Trial.

2

2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo.

Cicek M, Iwaniec UT, Goblirsch MJ, Vrabel A, Ruan M, Clohisy DR, Turner RR, Oursler MJ. Cicek M, et al. Among authors: ruan m. Cancer Res. 2007 Nov 1;67(21):10106-11. doi: 10.1158/0008-5472.CAN-07-1362. Cancer Res. 2007. PMID: 17974950

3

Novel pro-survival functions of the Kruppel-like transcription factor Egr2 in promotion of macrophage colony-stimulating factor-mediated osteoclast survival downstream of the MEK/ERK pathway.

Bradley EW, Ruan MM, Oursler MJ. Bradley EW, et al. Among authors: ruan mm. J Biol Chem. 2008 Mar 21;283(12):8055-64. doi: 10.1074/jbc.M709500200. Epub 2008 Jan 15. J Biol Chem. 2008. PMID: 18198176 Free article.

4

Pathway crosstalk between Ras/Raf and PI3K in promotion of M-CSF-induced MEK/ERK-mediated osteoclast survival.

Bradley EW, Ruan MM, Vrable A, Oursler MJ. Bradley EW, et al. Among authors: ruan mm. J Cell Biochem. 2008 Jul 1;104(4):1439-51. doi: 10.1002/jcb.21719. J Cell Biochem. 2008. PMID: 18275061 Free PMC article.

5

TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival.

Gingery A, Bradley EW, Pederson L, Ruan M, Horwood NJ, Oursler MJ. Gingery A, et al. Among authors: ruan m. Exp Cell Res. 2008 Sep 10;314(15):2725-38. doi: 10.1016/j.yexcr.2008.06.006. Epub 2008 Jun 13. Exp Cell Res. 2008. PMID: 18586026 Free PMC article.

6

PAK1 is a novel MEK-independent raf target controlling expression of the IAP survivin in M-CSF-mediated osteoclast survival.

Bradley EW, Ruan MM, Oursler MJ. Bradley EW, et al. Among authors: ruan mm. J Cell Physiol. 2008 Dec;217(3):752-8. doi: 10.1002/jcp.21550. J Cell Physiol. 2008. PMID: 18668521 Free PMC article.

7

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate.

Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ. Pederson L, et al. Among authors: ruan m. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20764-9. doi: 10.1073/pnas.0805133106. Epub 2008 Dec 15. Proc Natl Acad Sci U S A. 2008. PMID: 19075223 Free PMC article.

8

Transforming growth factor-{beta} coordinately induces suppressor of cytokine signaling 3 and leukemia inhibitory factor to suppress osteoclast apoptosis.

Ruan M, Pederson L, Bradley EW, Bamberger AM, Oursler MJ. Ruan M, et al. Endocrinology. 2010 Apr;151(4):1713-22. doi: 10.1210/en.2009-0813. Epub 2010 Feb 24. Endocrinology. 2010. PMID: 20181800 Free PMC article.

9

TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction.

Kumar A, Ruan M, Clifton K, Syed F, Khosla S, Oursler MJ. Kumar A, et al. Among authors: ruan m. Endocrinology. 2012 Jan;153(1):254-63. doi: 10.1210/en.2011-1169. Epub 2011 Nov 8. Endocrinology. 2012. PMID: 22067314 Free PMC article.

10

Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.

Quint P, Ruan M, Pederson L, Kassem M, Westendorf JJ, Khosla S, Oursler MJ. Quint P, et al. Among authors: ruan m. J Biol Chem. 2013 Feb 22;288(8):5398-406. doi: 10.1074/jbc.M112.413583. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23300082 Free PMC article.

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