Seddon B - Search Results

1

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.

Śledzińska A, Vila de Mucha M, Bergerhoff K, Hotblack A, Demane DF, Ghorani E, Akarca AU, Marzolini MAV, Solomon I, Vargas FA, Pule M, Ono M, Seddon B, Kassiotis G, Ariyan CE, Korn T, Marafioti T, Lord GM, Stauss H, Jenner RG, Peggs KS, Quezada SA. Śledzińska A, et al. Among authors: seddon b. Immunity. 2020 Jan 14;52(1):151-166.e6. doi: 10.1016/j.immuni.2019.12.007. Epub 2020 Jan 7. Immunity. 2020. PMID: 31924474 Free PMC article.

2

A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes.

Sinclair C, Ono M, Seddon B. Sinclair C, et al. Among authors: seddon b. Immunol Cell Biol. 2015 Apr;93(4):406-16. doi: 10.1038/icb.2014.107. Epub 2015 Jan 20. Immunol Cell Biol. 2015. PMID: 25601273

3

Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes.

Seddon B, Mason D. Seddon B, et al. J Exp Med. 1999 Jan 18;189(2):279-88. doi: 10.1084/jem.189.2.279. J Exp Med. 1999. PMID: 9892610 Free PMC article.

4

Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes.

Legname G, Seddon B, Lovatt M, Tomlinson P, Sarner N, Tolaini M, Williams K, Norton T, Kioussis D, Zamoyska R. Legname G, et al. Among authors: seddon b. Immunity. 2000 May;12(5):537-46. doi: 10.1016/s1074-7613(00)80205-8. Immunity. 2000. PMID: 10843386 Free article.

5

Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB.

Webb LV, Barbarulo A, Huysentruyt J, Vanden Berghe T, Takahashi N, Ley S, Vandenabeele P, Seddon B. Webb LV, et al. Among authors: seddon b. Immunity. 2019 Feb 19;50(2):348-361.e4. doi: 10.1016/j.immuni.2019.01.004. Epub 2019 Feb 5. Immunity. 2019. PMID: 30737145 Free PMC article.

6

NF-κB and Extrinsic Cell Death Pathways - Entwined Do-or-Die Decisions for T cells.

Blanchett S, Boal-Carvalho I, Layzell S, Seddon B. Blanchett S, et al. Among authors: seddon b. Trends Immunol. 2021 Jan;42(1):76-88. doi: 10.1016/j.it.2020.10.013. Epub 2020 Nov 24. Trends Immunol. 2021. PMID: 33246882 Free article. Review.

7

IKK promotes naïve T cell survival by repressing RIPK1-dependent apoptosis and activating NF-κB.

Carty F, Layzell S, Barbarulo A, Islam F, Webb LV, Seddon B. Carty F, et al. Among authors: seddon b. Sci Signal. 2023 Jun 27;16(791):eabo4094. doi: 10.1126/scisignal.abo4094. Epub 2023 Jun 27. Sci Signal. 2023. PMID: 37368952

8

The dynamics and longevity of circulating CD4+ memory T cells depend on cell age and not the chronological age of the host.

Bullock ME, Hogan T, Williams C, Morris S, Nowicka M, Sharjeel M, van Dorp C, Yates AJ, Seddon B. Bullock ME, et al. Among authors: seddon b. PLoS Biol. 2024 Aug 13;22(8):e3002380. doi: 10.1371/journal.pbio.3002380. eCollection 2024 Aug. PLoS Biol. 2024. PMID: 39137219 Free PMC article.

9

The role of subsets of CD4+ T cells in autoimmunity.

Fowell D, Powrie F, Saoudi A, Seddon B, Heath V, Mason D. Fowell D, et al. Among authors: seddon b. Ciba Found Symp. 1995;195:173-82; discussion 182-8. doi: 10.1002/9780470514849.ch12. Ciba Found Symp. 1995. PMID: 8724837 Review.

10

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells.

Seddon B, Tomlinson P, Zamoyska R. Seddon B, et al. Nat Immunol. 2003 Jul;4(7):680-6. doi: 10.1038/ni946. Epub 2003 Jun 15. Nat Immunol. 2003. PMID: 12808452

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