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11,075 results

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HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.
Zein J, Gaston B, Bazeley P, DeBoer MD, Igo RP Jr, Bleecker ER, Meyers D, Comhair S, Marozkina NV, Cotton C, Patel M, Alyamani M, Xu W, Busse WW, Calhoun WJ, Ortega V, Hawkins GA, Castro M, Chung KF, Fahy JV, Fitzpatrick AM, Israel E, Jarjour NN, Levy B, Mauger DT, Moore WC, Noel P, Peters SP, Teague WG, Wenzel SE, Erzurum SC, Sharifi N. Zein J, et al. Among authors: patel m. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2187-2193. doi: 10.1073/pnas.1918819117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932420 Free PMC article. Clinical Trial.
Deep androgen receptor suppression in prostate cancer exploits sexually dimorphic renal expression for systemic glucocorticoid exposure.
Alyamani M, Li J, Patel M, Taylor S, Nakamura F, Berk M, Przybycin C, Posadas EM, Madan RA, Gulley JL, Rini B, Garcia JA, Klein EA, Sharifi N. Alyamani M, et al. Among authors: patel m. Ann Oncol. 2020 Mar;31(3):369-376. doi: 10.1016/j.annonc.2019.12.002. Epub 2020 Feb 11. Ann Oncol. 2020. PMID: 32057540 Free PMC article.
Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer.
Kruse ML, Patel M, McManus J, Chung YM, Li X, Wei W, Bazeley PS, Nakamura F, Hardaway A, Downs E, Chandarlapaty S, Thomas M, Moore HC, Budd GT, Tang WHW, Hazen SL, Bernstein A, Nik-Zainal S, Abraham J, Sharifi N. Kruse ML, et al. Among authors: patel m. JCI Insight. 2021 Oct 22;6(20):e150403. doi: 10.1172/jci.insight.150403. JCI Insight. 2021. PMID: 34520399 Free PMC article.
Approaches to assessing 3β-hydroxysteroid dehydrogenase-1.
Alyamani M, McManus J, Patel M, Sharifi N. Alyamani M, et al. Among authors: patel m. Methods Enzymol. 2023;689:89-119. doi: 10.1016/bs.mie.2023.04.002. Epub 2023 Apr 25. Methods Enzymol. 2023. PMID: 37802584
Intratumoral androgen biosynthesis associated with 3β-hydroxysteroid dehydrogenase 1 promotes resistance to radiotherapy in prostate cancer.
Ganguly S, Lone Z, Muskara A, Imamura J, Hardaway A, Patel M, Berk M, Smile TD, Davicioni E, Stephans KL, Ciezki J, Weight CJ, Gupta S, Reddy CA, Tendulkar RD, Chakraborty AA, Klein EA, Sharifi N, Mian OY. Ganguly S, et al. Among authors: patel m. J Clin Invest. 2023 Nov 15;133(22):e165718. doi: 10.1172/JCI165718. J Clin Invest. 2023. PMID: 37966114 Free PMC article.
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