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Aging reduces liver resiliency by dysregulating Hedgehog signaling.
Maeso-Díaz R, Dalton GD, Oh S, Du K, Tang L, Chen T, Dutta RK, Hartman JH, Meyer JN, Diehl AM. Maeso-Díaz R, et al. Among authors: chen t. Aging Cell. 2022 Feb;21(2):e13530. doi: 10.1111/acel.13530. Epub 2022 Jan 4. Aging Cell. 2022. PMID: 34984806 Free PMC article.
Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.
Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, Denny TN, De Ussel MI, Satterwhite LL, Ko ER, Ginsburg GS, Kraft BD, Tsalik EL, Shen X, Woods CW. Giroux NS, et al. Among authors: chen t. Sci Rep. 2022 Jul 9;12(1):11714. doi: 10.1038/s41598-022-15668-8. Sci Rep. 2022. PMID: 35810186 Free PMC article.
Integrated chromatin and transcriptomic profiling of patient-derived colon cancer organoids identifies personalized drug targets to overcome oxaliplatin resistance.
Tung KL, Chen KY, Negrete M, Chen T, Safi A, Aljamal AA, Song L, Crawford GE, Ding S, Hsu DS, Shen X. Tung KL, et al. Among authors: chen ky, chen t. Genes Dis. 2019 Oct 29;8(2):203-214. doi: 10.1016/j.gendis.2019.10.012. eCollection 2021 Mar. Genes Dis. 2019. PMID: 33997167 Free PMC article.
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
Wang L, Wang E, Prado Balcazar J, Wu Z, Xiang K, Wang Y, Huang Q, Negrete M, Chen KY, Li W, Fu Y, Dohlman A, Mines R, Zhang L, Kobayashi Y, Chen T, Shi G, Shen JP, Kopetz S, Tata PR, Moreno V, Gersbach C, Crawford G, Hsu D, Huang E, Bu P, Shen X. Wang L, et al. Among authors: chen ky, chen t. Adv Sci (Weinh). 2021 Oct;8(19):e2004673. doi: 10.1002/advs.202004673. Epub 2021 Aug 10. Adv Sci (Weinh). 2021. PMID: 34378358 Free PMC article.
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