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Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.
Clark AD, Nair N, Anderson AE, Thalayasingam N, Naamane N, Skelton AJ, Diboll J, Barton A, Eyre S, Isaacs JD, Pratt AG, Reynard LN. Clark AD, et al. Among authors: isaacs jd. J Allergy Clin Immunol. 2020 May;145(5):1438-1451. doi: 10.1016/j.jaci.2019.12.910. Epub 2020 Jan 13. J Allergy Clin Immunol. 2020. PMID: 31945409 Free PMC article.
Tregs and rheumatoid arthritis.
Anderson AE, Isaacs JD. Anderson AE, et al. Among authors: isaacs jd. Acta Reumatol Port. 2008 Jan-Mar;33(1):17-33. Acta Reumatol Port. 2008. PMID: 18344919 Free article. Review.
Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis.
Maxwell JR, Potter C, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG. Maxwell JR, et al. Among authors: isaacs jd. Hum Mol Genet. 2008 Nov 15;17(22):3532-8. doi: 10.1093/hmg/ddn245. Epub 2008 Aug 19. Hum Mol Genet. 2008. PMID: 18713756
Current concepts in the pathogenesis of early rheumatoid arthritis.
Pratt AG, Isaacs JD, Mattey DL. Pratt AG, et al. Among authors: isaacs jd. Best Pract Res Clin Rheumatol. 2009 Feb;23(1):37-48. doi: 10.1016/j.berh.2008.08.002. Best Pract Res Clin Rheumatol. 2009. PMID: 19233044 Free PMC article. Review.
Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.
Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS. Bowes JD, et al. Among authors: isaacs jd. Pharmacogenet Genomics. 2009 Apr;19(4):319-23. doi: 10.1097/FPC.0b013e328328d51f. Pharmacogenet Genomics. 2009. PMID: 19262425
Regulatory T cells and autoimmunity.
Vila J, Isaacs JD, Anderson AE. Vila J, et al. Among authors: isaacs jd. Curr Opin Hematol. 2009 Jul;16(4):274-9. doi: 10.1097/MOH.0b013e32832a9a01. Curr Opin Hematol. 2009. PMID: 19417650 Review.
375 results