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Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction.
Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, González A, Thum T. Schimmel K, et al. Among authors: pfanne a. Circulation. 2020 Mar 3;141(9):751-767. doi: 10.1161/CIRCULATIONAHA.119.042559. Epub 2020 Jan 17. Circulation. 2020. PMID: 31948273 Free PMC article.
Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology.
Schimmel K, Stojanović SD, Huang CK, Jung M, Meyer MH, Xiao K, Grote-Levi L, Bär C, Pfanne A, Mitzka S, Just A, Geffers R, Bock K, Kenneweg F, Kleemiß F, Falk CS, Fiedler J, Thum T. Schimmel K, et al. Among authors: pfanne a. J Mol Cell Cardiol. 2021 Jan;150:91-100. doi: 10.1016/j.yjmcc.2020.10.008. Epub 2020 Oct 28. J Mol Cell Cardiol. 2021. PMID: 33127387 Free article.
MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.
Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T. Hartmann D, et al. Among authors: pfanne a. Circulation. 2016 Dec 13;134(24):1973-1990. doi: 10.1161/CIRCULATIONAHA.116.022478. Epub 2016 Oct 25. Circulation. 2016. PMID: 27780851
Blood-based microRNA profiling in patients with cardiac amyloidosis.
Derda AA, Pfanne A, Bär C, Schimmel K, Kennel PJ, Xiao K, Schulze PC, Bauersachs J, Thum T. Derda AA, et al. Among authors: pfanne a. PLoS One. 2018 Oct 17;13(10):e0204235. doi: 10.1371/journal.pone.0204235. eCollection 2018. PLoS One. 2018. PMID: 30332417 Free PMC article.
Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis.
Kenneweg F, Bang C, Xiao K, Boulanger CM, Loyer X, Mazlan S, Schroen B, Hermans-Beijnsberger S, Foinquinos A, Hirt MN, Eschenhagen T, Funcke S, Stojanovic S, Genschel C, Schimmel K, Just A, Pfanne A, Scherf K, Dehmel S, Raemon-Buettner SM, Fiedler J, Thum T. Kenneweg F, et al. Among authors: pfanne a. Mol Ther Nucleic Acids. 2019 Dec 6;18:363-374. doi: 10.1016/j.omtn.2019.09.003. Epub 2019 Sep 13. Mol Ther Nucleic Acids. 2019. PMID: 31634682 Free PMC article.
Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization.
Fiedler J, Breckwoldt K, Remmele CW, Hartmann D, Dittrich M, Pfanne A, Just A, Xiao K, Kunz M, Müller T, Hansen A, Geffers R, Dandekar T, Eschenhagen T, Thum T. Fiedler J, et al. Among authors: pfanne a. J Am Coll Cardiol. 2015 Nov 3;66(18):2005-2015. doi: 10.1016/j.jacc.2015.07.081. J Am Coll Cardiol. 2015. PMID: 26516004 Free PMC article.
28 results