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A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers.
Angel CZ, Beattie S, Hanif EAM, Ryan MP, Guerra Liberal FDC, Zhang SD, Monteith S, Buckley NE, Parker E, Haynes S, McIntyre AJ, Haddock P, Sharifova M, Branco CM, Mullan PB. Angel CZ, et al. Cell Commun Signal. 2024 Sep 26;22(1):454. doi: 10.1186/s12964-024-01793-6. Cell Commun Signal. 2024. PMID: 39327614 Free PMC article.
TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers.
McIntyre AJ, Angel CZ, Smith JS, Templeman A, Beattie K, Beattie S, Ormrod A, Devlin E, McGreevy C, Bothwell C, Eddie SL, Buckley NE, Williams R, Mullan PB. McIntyre AJ, et al. Among authors: angel cz. Nucleic Acids Res. 2022 Jun 24;50(11):6154-6173. doi: 10.1093/nar/gkac494. Nucleic Acids Res. 2022. PMID: 35687133 Free PMC article.