Cieplak P - Search Results

1

The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites.

Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, Linington RG, Long JZ, Uhlemann AC, Weerapana E, Fidock DA, Bogyo M. Yoo E, et al. Among authors: cieplak p. Cell Chem Biol. 2020 Feb 20;27(2):143-157.e5. doi: 10.1016/j.chembiol.2020.01.001. Epub 2020 Jan 23. Cell Chem Biol. 2020. PMID: 31978322 Free PMC article.

2

Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host.

Onguka O, Babin BM, Lakemeyer M, Foe IT, Amara N, Terrell SM, Lum KM, Cieplak P, Niphakis MJ, Long JZ, Bogyo M. Onguka O, et al. Among authors: cieplak p. Cell Chem Biol. 2021 Oct 21;28(10):1501-1513.e5. doi: 10.1016/j.chembiol.2021.05.001. Epub 2021 May 26. Cell Chem Biol. 2021. PMID: 34043961 Free PMC article.

3

Determining the atomic charge of calcium ion requires the information of its coordination geometry in an EF-hand motif.

Zhang P, Han J, Cieplak P, Cheung MS. Zhang P, et al. Among authors: cieplak p. J Chem Phys. 2021 Mar 28;154(12):124104. doi: 10.1063/5.0037517. J Chem Phys. 2021. PMID: 33810667 Free PMC article.

4

Selective and potent furin inhibitors protect cells from anthrax without significant toxicity.

Remacle AG, Gawlik K, Golubkov VS, Cadwell GW, Liddington RC, Cieplak P, Millis SZ, Desjardins R, Routhier S, Yuan XW, Neugebauer WA, Day R, Strongin AY. Remacle AG, et al. Among authors: cieplak p. Int J Biochem Cell Biol. 2010 Jun;42(6):987-95. doi: 10.1016/j.biocel.2010.02.013. Epub 2010 Mar 1. Int J Biochem Cell Biol. 2010. PMID: 20197107 Free PMC article.

5

New details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assay.

Shiryaev SA, Thomsen ER, Cieplak P, Chudin E, Cheltsov AV, Chee MS, Kozlov IA, Strongin AY. Shiryaev SA, et al. Among authors: cieplak p. PLoS One. 2012;7(4):e35759. doi: 10.1371/journal.pone.0035759. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558217 Free PMC article.

6

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.

Remacle AG, Cieplak P, Nam DH, Shiryaev SA, Ge X, Strongin AY. Remacle AG, et al. Among authors: cieplak p. Oncotarget. 2017 Jan 10;8(2):2781-2799. doi: 10.18632/oncotarget.13157. Oncotarget. 2017. PMID: 27835863 Free PMC article.

7

Synthesis of novel beta-lactone inhibitors of fatty acid synthase.

Richardson RD, Ma G, Oyola Y, Zancanella M, Knowles LM, Cieplak P, Romo D, Smith JW. Richardson RD, et al. Among authors: cieplak p. J Med Chem. 2008 Sep 11;51(17):5285-96. doi: 10.1021/jm800321h. Epub 2008 Aug 19. J Med Chem. 2008. PMID: 18710210 Free PMC article.

8

Matrix metalloproteinase proteolysis of the mycobacterial HSP65 protein as a potential source of immunogenic peptides in human tuberculosis.

Shiryaev SA, Cieplak P, Aleshin AE, Sun Q, Zhu W, Motamedchaboki K, Sloutsky A, Strongin AY. Shiryaev SA, et al. Among authors: cieplak p. FEBS J. 2011 Sep;278(18):3277-86. doi: 10.1111/j.1742-4658.2011.08244.x. Epub 2011 Aug 8. FEBS J. 2011. PMID: 21752195 Free PMC article.

9

High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family.

Kukreja M, Shiryaev SA, Cieplak P, Muranaka N, Routenberg DA, Chernov AV, Kumar S, Remacle AG, Smith JW, Kozlov IA, Strongin AY. Kukreja M, et al. Among authors: cieplak p. Chem Biol. 2015 Aug 20;22(8):1122-33. doi: 10.1016/j.chembiol.2015.07.008. Epub 2015 Aug 6. Chem Biol. 2015. PMID: 26256476 Free PMC article.

10

Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island.

Shiryaev SA, Aleshin AE, Muranaka N, Kukreja M, Routenberg DA, Remacle AG, Liddington RC, Cieplak P, Kozlov IA, Strongin AY. Shiryaev SA, et al. Among authors: cieplak p. FEBS J. 2014 Jun;281(11):2487-502. doi: 10.1111/febs.12804. Epub 2014 Apr 22. FEBS J. 2014. PMID: 24698179 Free PMC article.

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