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Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L. Sun X, et al. Among authors: ni z. Nat Commun. 2020 Jan 24;11(1):479. doi: 10.1038/s41467-019-14169-z. Nat Commun. 2020. PMID: 31980602 Free PMC article.
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Wang Q, Tan QY, Xu W, Qi HB, Chen D, Zhou S, Ni ZH, Kuang L, Guo JY, Huang JL, Wang XX, Wang ZQ, Su N, Chen L, Chen B, Jiang WL, Gao Y, Chen HG, Du XL, Xie YL, Chen L. Wang Q, et al. Among authors: ni zh. Osteoarthritis Cartilage. 2017 Nov;25(11):1868-1879. doi: 10.1016/j.joca.2017.07.010. Epub 2017 Jul 14. Osteoarthritis Cartilage. 2017. PMID: 28716756 Free PMC article.
A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice.
Tan Q, Chen B, Wang Q, Xu W, Wang Y, Lin Z, Luo F, Huang S, Zhu Y, Su N, Jin M, Li C, Kuang L, Qi H, Ni Z, Wang Z, Luo X, Jiang W, Chen H, Chen S, Li F, Zhang B, Huang J, Zhang R, Jin K, Xu X, Deng C, Du X, Xie Y, Chen L. Tan Q, et al. Among authors: ni z. Osteoarthritis Cartilage. 2018 Dec;26(12):1733-1743. doi: 10.1016/j.joca.2018.08.012. Epub 2018 Sep 8. Osteoarthritis Cartilage. 2018. PMID: 30201491 Free article.
Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model.
Luo F, Xie Y, Wang Z, Huang J, Tan Q, Sun X, Li F, Li C, Liu M, Zhang D, Xu M, Su N, Ni Z, Jiang W, Chang J, Chen H, Chen S, Xu X, Deng C, Wang Z, Du X, Chen L. Luo F, et al. Among authors: ni z. Mol Ther Nucleic Acids. 2018 Dec 7;13:291-302. doi: 10.1016/j.omtn.2018.09.012. Epub 2018 Sep 22. Mol Ther Nucleic Acids. 2018. PMID: 30321816 Free PMC article.
Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis.
Chen B, Tan Q, Chen H, Luo F, Xu M, Zhao J, Liu P, Sun X, Su N, Zhang D, Fan W, Liu M, Huang H, Wang Z, Huang J, Zhang R, Li C, Li F, Ni Z, Du X, Jin M, Yang J, Xie Y, Chen L. Chen B, et al. Among authors: ni z. J Orthop Translat. 2019 Jan 7;17:103-111. doi: 10.1016/j.jot.2018.12.001. eCollection 2019 Apr. J Orthop Translat. 2019. PMID: 31194037 Free PMC article.
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling.
Sun X, Zhang R, Liu M, Chen H, Chen L, Luo F, Zhang D, Huang J, Li F, Ni Z, Qi H, Su N, Jin M, Yang J, Tan Q, Du X, Chen B, Huang H, Chen S, Yin L, Xu X, Deng C, Luo L, Xie Y, Chen L. Sun X, et al. Among authors: ni z. J Bone Miner Res. 2019 Nov;34(11):2101-2116. doi: 10.1002/jbmr.3820. Epub 2019 Sep 4. J Bone Miner Res. 2019. PMID: 31237961 Free article.
2,948 results