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Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo.
Tora G, Kim SH, Pi Z, Johnson JA, Jiang J, Phillips M, Lloyd J, Abell LM, Lu H, Locke G, Adam LP, Taylor DS, Yin X, Behnia K, Zhao L, Yang R, Basso M, Caporuscio C, Chen AY, Liu E, Kirshgessner T, Onorato JM, Ryan C, Traeger SC, Gordon D, Wexler RR, Finlay HJ. Tora G, et al. Among authors: chen ay. J Med Chem. 2020 Feb 27;63(4):1660-1670. doi: 10.1021/acs.jmedchem.9b01831. Epub 2020 Feb 11. J Med Chem. 2020. PMID: 31990537
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.
Johnson JA, Tora G, Pi Z, Phillips M, Yin X, Yang R, Zhao L, Chen AY, Taylor DS, Basso M, Rose A, Behnia K, Onorato J, Chen XQ, Abell LM, Lu H, Locke G, Caporuscio C, Galella M, Adam LP, Gordon D, Wexler RR, Finlay HJ. Johnson JA, et al. Among authors: chen ay, chen xq. ACS Med Chem Lett. 2018 Nov 21;9(12):1263-1268. doi: 10.1021/acsmedchemlett.8b00424. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613337 Free PMC article.
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Hu Z, Wang C, Glunz PW, Li J, Cheadle NL, Chen AY, Chen XQ, Myers JE, Guarino VR, Rose A, Sack JS, Sitkoff D, Taylor DS, Xu S, Yan C, Zhang H, Zhang L, Hennan J, Adam LP, Wexler RR, Quan ML. Hu Z, et al. Among authors: chen ay, chen xq. Bioorg Med Chem Lett. 2020 Nov 1;30(21):127495. doi: 10.1016/j.bmcl.2020.127495. Epub 2020 Aug 13. Bioorg Med Chem Lett. 2020. PMID: 32798651
Differential Ultrasound Rates Mirror Sex Disparities in Thyroid Cancer.
Fernandes-Taylor S, Bowles EJA, Venkatesh M, Doud R, Krebsbach C, Arroyo N, Hanlon B, Chen AY, Davies L, Francis DO. Fernandes-Taylor S, et al. Among authors: chen ay. Thyroid. 2024 Dec;34(12):1531-1539. doi: 10.1089/thy.2024.0344. Epub 2024 Nov 28. Thyroid. 2024. PMID: 39607408
Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG.
Bellier JP, Román Viera AM, Christiano C, Anzai JAU, Moreno S, Campbell EC, Godwin L, Li A, Chen AY, Alam SM, Saba A, Yoo HB, Yang HS, Chhatwal JP, Selkoe DJ, Liu L. Bellier JP, et al. Among authors: chen ay. Ann Clin Transl Neurol. 2024 Dec;11(12):3192-3204. doi: 10.1002/acn3.52227. Epub 2024 Oct 30. Ann Clin Transl Neurol. 2024. PMID: 39476320 Free PMC article.
Response.
Yerke JR, Mireles-Cabodevila E, Chen AY, Bass SN, Reddy AJ, Bauer SR, Kokoczka L, Dugar S, Moghekar A. Yerke JR, et al. Among authors: chen ay. Chest. 2024 Aug;166(2):e70-e71. doi: 10.1016/j.chest.2024.03.036. Chest. 2024. PMID: 39122314 No abstract available.
688 results