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Page 1
Primary pulmonary arterial hypertension: Protocol to assess comprehensively in the rat the response to pharmacologic treatments.
Novelli D, Fumagalli F, Staszewsky L, Ristagno G, Olivari D, Masson S, De Giorgio D, Ceriani S, Massafra R, De Logu F, Nassini R, Milioli M, Facchinetti F, Cantoni S, Trevisani M, Letizia T, Russo I, Salio M, Latini R. Novelli D, et al. Among authors: facchinetti f. MethodsX. 2019 Dec 19;7:100771. doi: 10.1016/j.mex.2019.100771. eCollection 2020. MethodsX. 2019. PMID: 31993338 Free PMC article.
Monocrotaline-induced pulmonary arterial hypertension: Time-course of injury and comparative evaluation of macitentan and Y-27632, a Rho kinase inhibitor.
Novelli D, Fumagalli F, Staszewsky L, Ristagno G, Olivari D, Masson S, De Giorgio D, Ceriani S, Affatato R, De Logu F, Nassini R, Milioli M, Facchinetti F, Cantoni S, Trevisani M, Letizia T, Russo I, Salio M, Latini R. Novelli D, et al. Among authors: facchinetti f. Eur J Pharmacol. 2019 Dec 15;865:172777. doi: 10.1016/j.ejphar.2019.172777. Epub 2019 Nov 4. Eur J Pharmacol. 2019. PMID: 31697933
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
Nassini R, Pedretti P, Moretto N, Fusi C, Carnini C, Facchinetti F, Viscomi AR, Pisano AR, Stokesberry S, Brunmark C, Svitacheva N, McGarvey L, Patacchini R, Damholt AB, Geppetti P, Materazzi S. Nassini R, et al. Among authors: facchinetti f. PLoS One. 2012;7(8):e42454. doi: 10.1371/journal.pone.0042454. Epub 2012 Aug 14. PLoS One. 2012. PMID: 22905134 Free PMC article.
Discovery and Optimization of Thiazolidinyl and Pyrrolidinyl Derivatives as Inhaled PDE4 Inhibitors for Respiratory Diseases.
Carzaniga L, Amari G, Rizzi A, Capaldi C, De Fanti R, Ghidini E, Villetti G, Carnini C, Moretto N, Facchinetti F, Caruso P, Marchini G, Battipaglia L, Patacchini R, Cenacchi V, Volta R, Amadei F, Pappani A, Capacchi S, Bagnacani V, Delcanale M, Puccini P, Catinella S, Civelli M, Armani E. Carzaniga L, et al. Among authors: facchinetti f. J Med Chem. 2017 Dec 28;60(24):10026-10046. doi: 10.1021/acs.jmedchem.7b01044. Epub 2017 Dec 14. J Med Chem. 2017. PMID: 29200281
CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.
Martucci C, Allen AD, Moretto N, Bagnacani V, Fioni A, Patacchini R, Civelli M, Villetti G, Facchinetti F. Martucci C, et al. Among authors: facchinetti f. Front Pharmacol. 2024 Mar 14;15:1343941. doi: 10.3389/fphar.2024.1343941. eCollection 2024. Front Pharmacol. 2024. PMID: 38549671 Free PMC article.
1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
Imbimbo BP, Del Giudice E, Colavito D, D'Arrigo A, Dalle Carbonare M, Villetti G, Facchinetti F, Volta R, Pietrini V, Baroc MF, Serneels L, De Strooper B, Leon A. Imbimbo BP, et al. Among authors: facchinetti f. J Pharmacol Exp Ther. 2007 Dec;323(3):822-30. doi: 10.1124/jpet.107.129007. Epub 2007 Sep 25. J Pharmacol Exp Ther. 2007. PMID: 17895400
773 results