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Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice.
Choi BS, Daniel N, Houde VP, Ouellette A, Marcotte B, Varin TV, Vors C, Feutry P, Ilkayeva O, Ståhlman M, St-Pierre P, Bäckhed F, Tremblay A, White PJ, Marette A. Choi BS, et al. Among authors: stahlman m. Nat Commun. 2021 Jun 7;12(1):3377. doi: 10.1038/s41467-021-23782-w. Nat Commun. 2021. PMID: 34099716 Free PMC article.
Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.
Nuñez-Durán E, Aghajan M, Amrutkar M, Sütt S, Cansby E, Booten SL, Watt A, Ståhlman M, Stefan N, Häring HU, Staiger H, Borén J, Marschall HU, Mahlapuu M. Nuñez-Durán E, et al. Among authors: stahlman m. Hepatol Commun. 2017 Nov 20;2(1):69-83. doi: 10.1002/hep4.1128. eCollection 2018 Jan. Hepatol Commun. 2017. PMID: 29404514 Free PMC article.
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance.
Roumans KHM, Lindeboom L, Veeraiah P, Remie CME, Phielix E, Havekes B, Bruls YMH, Brouwers MCGJ, Ståhlman M, Alssema M, Peters HPF, de Mutsert R, Staels B, Taskinen MR, Borén J, Schrauwen P, Schrauwen-Hinderling VB. Roumans KHM, et al. Among authors: stahlman m. Nat Commun. 2020 Apr 20;11(1):1891. doi: 10.1038/s41467-020-15684-0. Nat Commun. 2020. PMID: 32312974 Free PMC article.
Microbiota-induced obesity requires farnesoid X receptor.
Parséus A, Sommer N, Sommer F, Caesar R, Molinaro A, Ståhlman M, Greiner TU, Perkins R, Bäckhed F. Parséus A, et al. Among authors: stahlman m. Gut. 2017 Mar;66(3):429-437. doi: 10.1136/gutjnl-2015-310283. Epub 2016 Jan 6. Gut. 2017. PMID: 26740296 Free PMC article.
Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.
Fuchs CD, Dixon ED, Hendrikx T, Mlitz V, Wahlström A, Ståhlman M, Scharnagl H, Stojakovic T, Binder CJ, Marschall HU, Trauner M. Fuchs CD, et al. Among authors: stahlman m. Hepatol Commun. 2022 Sep;6(9):2368-2378. doi: 10.1002/hep4.1998. Epub 2022 Jun 12. Hepatol Commun. 2022. PMID: 35691019 Free PMC article.
286 results