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The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.
Søndergaard MT, Liu Y, Larsen KT, Nani A, Tian X, Holt C, Wang R, Wimmer R, Van Petegem F, Fill M, Chen SR, Overgaard MT. Søndergaard MT, et al. Among authors: wimmer r. J Biol Chem. 2017 Jan 27;292(4):1385-1395. doi: 10.1074/jbc.M116.766253. Epub 2016 Dec 7. J Biol Chem. 2017. PMID: 27927985 Free PMC article.
The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
Holt C, Hamborg L, Lau K, Brohus M, Sørensen AB, Larsen KT, Sommer C, Van Petegem F, Overgaard MT, Wimmer R. Holt C, et al. Among authors: wimmer r. J Biol Chem. 2020 May 29;295(22):7620-7634. doi: 10.1074/jbc.RA120.013430. Epub 2020 Apr 21. J Biol Chem. 2020. PMID: 32317284 Free PMC article.
Real-time imaging of the growth-inhibitory effect of JS399-19 on Fusarium.
Wollenberg RD, Donau SS, Nielsen TT, Sørensen JL, Giese H, Wimmer R, Søndergaard TE. Wollenberg RD, et al. Among authors: wimmer r. Pestic Biochem Physiol. 2016 Nov;134:24-30. doi: 10.1016/j.pestbp.2016.05.002. Epub 2016 May 14. Pestic Biochem Physiol. 2016. PMID: 27914536
266 results