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An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector Anopheles funestus Reveals a Loss of Bed Nets Efficacy Associated with GSTe2 Metabolic Resistance.
Menze BD, Kouamo MF, Wondji MJ, Tchapga W, Tchoupo M, Kusimo MO, Mouhamadou CS, Riveron JM, Wondji CS. Menze BD, et al. Among authors: kouamo mf. Genes (Basel). 2020 Jan 29;11(2):143. doi: 10.3390/genes11020143. Genes (Basel). 2020. PMID: 32013227 Free PMC article.
Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa.
Kouamo MFM, Ibrahim SS, Hearn J, Riveron JM, Kusimo M, Tchouakui M, Ebai T, Tchapga W, Wondji MJ, Irving H, Boudjeko T, Boyom FF, Wondji CS. Kouamo MFM, et al. Genes (Basel). 2021 Apr 13;12(4):561. doi: 10.3390/genes12040561. Genes (Basel). 2021. PMID: 33924421 Free PMC article.
Two highly selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b genes drive pyrethroid resistance in Anopheles funestus in West Africa.
Tatchou-Nebangwa NMT, Mugenzi LMJ, Muhammad A, Nebangwa DN, Kouamo MFM, Tagne CSD, Tekoh TA, Tchouakui M, Ghogomu SM, Ibrahim SS, Wondji CS. Tatchou-Nebangwa NMT, et al. Among authors: kouamo mfm. BMC Biol. 2024 Dec 18;22(1):286. doi: 10.1186/s12915-024-02081-y. BMC Biol. 2024. PMID: 39696366 Free PMC article.
A single mutation G454A in the P450 CYP9K1 drives pyrethroid resistance in the major malaria vector Anopheles funestus reducing bed net efficacy.
Djoko Tagne CS, Kouamo MFM, Tchouakui M, Muhammad A, Mugenzi LJL, Tatchou-Nebangwa NMT, Thiomela RF, Gadji M, Wondji MJ, Hearn J, Desire MH, Ibrahim SS, Wondji CS. Djoko Tagne CS, et al. Among authors: kouamo mfm. Genetics. 2024 Nov 7:iyae181. doi: 10.1093/genetics/iyae181. Online ahead of print. Genetics. 2024. PMID: 39509710
Functional Validation of Endogenous Redox Partner Cytochrome P450 Reductase Reveals the Key P450s CYP6P9a/-b as Broad Substrate Metabolizers Conferring Cross-Resistance to Different Insecticide Classes in Anopheles funestus.
Ibrahim SS, Kouamo MFM, Muhammad A, Irving H, Riveron JM, Tchouakui M, Wondji CS. Ibrahim SS, et al. Among authors: kouamo mfm. Int J Mol Sci. 2024 Jul 25;25(15):8092. doi: 10.3390/ijms25158092. Int J Mol Sci. 2024. PMID: 39125661 Free PMC article.