Lowell AN - Search Results

1

Control of Stereoselectivity in Diverse Hapalindole Metabolites is Mediated by Cofactor-Induced Combinatorial Pairing of Stig Cyclases.

Li S, Newmister SA, Lowell AN, Zi J, Chappell CR, Yu F, Hohlman RM, Orjala J, Williams RM, Sherman DH. Li S, et al. Among authors: lowell an. Angew Chem Int Ed Engl. 2020 May 18;59(21):8166-8172. doi: 10.1002/anie.201913686. Epub 2020 Mar 19. Angew Chem Int Ed Engl. 2020. PMID: 32052896 Free PMC article.

2

Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries.

Lowell AN, Santoro N, Swaney SM, McQuade TJ, Schultz PJ, Larsen MJ, Sherman DH. Lowell AN, et al. Chem Biol Drug Des. 2015 Dec;86(6):1331-8. doi: 10.1111/cbdd.12614. Epub 2015 Jul 25. Chem Biol Drug Des. 2015. PMID: 26147927 Free PMC article.

3

Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade.

Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH. Li S, et al. Among authors: lowell an. J Am Chem Soc. 2015 Dec 16;137(49):15366-9. doi: 10.1021/jacs.5b10136. Epub 2015 Dec 2. J Am Chem Soc. 2015. PMID: 26629885 Free PMC article.

4

Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway.

DeMars MD 2nd, Sheng F, Park SR, Lowell AN, Podust LM, Sherman DH. DeMars MD 2nd, et al. Among authors: lowell an. ACS Chem Biol. 2016 Sep 16;11(9):2642-54. doi: 10.1021/acschembio.6b00479. Epub 2016 Aug 5. ACS Chem Biol. 2016. PMID: 27420774 Free PMC article.

5

Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.

Koryakina I, Kasey C, McArthur JB, Lowell AN, Chemler JA, Li S, Hansen DA, Sherman DH, Williams GJ. Koryakina I, et al. Among authors: lowell an. ACS Chem Biol. 2017 Jan 20;12(1):114-123. doi: 10.1021/acschembio.6b00732. Epub 2016 Nov 29. ACS Chem Biol. 2017. PMID: 28103677 Free PMC article.

6

Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids.

Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH. Li S, et al. Among authors: lowell an. Nat Chem Biol. 2017 May;13(5):467-469. doi: 10.1038/nchembio.2327. Epub 2017 Mar 13. Nat Chem Biol. 2017. PMID: 28288107 Free PMC article.

7

Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization.

Lowell AN, DeMars MD 2nd, Slocum ST, Yu F, Anand K, Chemler JA, Korakavi N, Priessnitz JK, Park SR, Koch AA, Schultz PJ, Sherman DH. Lowell AN, et al. J Am Chem Soc. 2017 Jun 14;139(23):7913-7920. doi: 10.1021/jacs.7b02875. Epub 2017 Jun 5. J Am Chem Soc. 2017. PMID: 28525276 Free PMC article.

8

Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.

Newmister SA, Li S, Garcia-Borràs M, Sanders JN, Yang S, Lowell AN, Yu F, Smith JL, Williams RM, Houk KN, Sherman DH. Newmister SA, et al. Among authors: lowell an. Nat Chem Biol. 2018 Apr;14(4):345-351. doi: 10.1038/s41589-018-0003-x. Epub 2018 Mar 12. Nat Chem Biol. 2018. PMID: 29531360 Free PMC article.

9

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module.

Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. Among authors: lowell an. ACS Chem Biol. 2018 Jun 15;13(6):1640-1650. doi: 10.1021/acschembio.8b00252. Epub 2018 May 8. ACS Chem Biol. 2018. PMID: 29701944 Free PMC article.

10

Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway.

Slocum ST, Lowell AN, Tripathi A, Shende VV, Smith JL, Sherman DH. Slocum ST, et al. Among authors: lowell an. Methods Enzymol. 2018;604:207-236. doi: 10.1016/bs.mie.2018.01.034. Epub 2018 Apr 9. Methods Enzymol. 2018. PMID: 29779653 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

29 results

Search Page

Filters