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EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
Struve N, Binder ZA, Stead LF, Brend T, Bagley SJ, Faulkner C, Ott L, Müller-Goebel J, Weik AS, Hoffer K, Krug L, Rieckmann T, Bußmann L, Henze M, Morrissette JJD, Kurian KM, Schüller U, Petersen C, Rothkamm K, O Rourke DM, Short SC, Kriegs M. Struve N, et al. Among authors: kurian km. Oncogene. 2020 Apr;39(15):3041-3055. doi: 10.1038/s41388-020-1208-5. Epub 2020 Feb 17. Oncogene. 2020. PMID: 32066879 Free PMC article.
EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.
Faulkner C, Palmer A, Williams H, Wragg C, Haynes HR, White P, DeSouza RM, Williams M, Hopkins K, Kurian KM. Faulkner C, et al. Among authors: kurian km. Br J Neurosurg. 2015 Feb;29(1):23-29. doi: 10.3109/02688697.2014.950631. Epub 2014 Aug 20. Br J Neurosurg. 2015. PMID: 25141189
BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.
Faulkner C, Ellis HP, Shaw A, Penman C, Palmer A, Wragg C, Greenslade M, Haynes HR, Williams H, Lowis S, White P, Williams M, Capper D, Kurian KM. Faulkner C, et al. Among authors: kurian km. J Neuropathol Exp Neurol. 2015 Sep;74(9):867-72. doi: 10.1097/NEN.0000000000000226. J Neuropathol Exp Neurol. 2015. PMID: 26222501 Free PMC article.
shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
Haynes HR, Scott HL, Killick-Cole CL, Shaw G, Brend T, Hares KM, Redondo J, Kemp KC, Ballesteros LS, Herman A, Cordero-Llana O, Singleton WG, Mills F, Batstone T, Bulstrode H, Kauppinen RA, Wurdak H, Uney JB, Short SC, Wilkins A, Kurian KM. Haynes HR, et al. Among authors: kurian km. J Pathol. 2019 Apr;247(4):422-434. doi: 10.1002/path.5201. Epub 2018 Dec 27. J Pathol. 2019. PMID: 30565681 Free PMC article.
Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.
McAleenan A, Kelly C, Spiga F, Kernohan A, Cheng HY, Dawson S, Schmidt L, Robinson T, Brandner S, Faulkner CL, Wragg C, Jefferies S, Howell A, Vale L, Higgins JPT, Kurian KM. McAleenan A, et al. Among authors: kurian km. Cochrane Database Syst Rev. 2021 Mar 12;3(3):CD013316. doi: 10.1002/14651858.CD013316.pub2. Cochrane Database Syst Rev. 2021. PMID: 33710615 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33942105
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
Brandner S, McAleenan A, Kelly C, Spiga F, Cheng HY, Dawson S, Schmidt L, Faulkner CL, Wragg C, Jefferies S, Higgins JPT, Kurian KM. Brandner S, et al. Among authors: kurian km. Neuro Oncol. 2021 Sep 1;23(9):1457-1469. doi: 10.1093/neuonc/noab105. Neuro Oncol. 2021. PMID: 34467991 Free PMC article.
106 results