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Page 1
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, van Loo G. Verboom L, et al. Among authors: roels j. Cell Rep. 2020 Feb 18;30(7):2237-2247.e6. doi: 10.1016/j.celrep.2020.01.028. Cell Rep. 2020. PMID: 32075762 Free article.
Fibrotic enzymes modulate wound-induced skin tumorigenesis.
Van Hove L, Lecomte K, Roels J, Vandamme N, Vikkula HK, Hoorens I, Ongenae K, Hochepied T, Donati G, Saeys Y, Quist SR, Watt FM, van Loo G, Hoste E. Van Hove L, et al. Among authors: roels j. EMBO Rep. 2021 May 5;22(5):e51573. doi: 10.15252/embr.202051573. Epub 2021 Mar 29. EMBO Rep. 2021. PMID: 33780134 Free PMC article.
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, Verboom L, Vikkula HK, Sze M, Van Hove L, Verstaen K, Martens A, Hochepied T, Saeys Y, Ravichandran K, Kasper M, van Loo G. Hoste E, et al. Among authors: roels j. Nat Commun. 2021 Oct 8;12(1):5913. doi: 10.1038/s41467-021-25944-2. Nat Commun. 2021. PMID: 34625556 Free PMC article.
Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation.
Van Hove L, Toniolo A, Ghiasloo M, Lecomte K, Boone F, Ciers M, Raaijmakers K, Vandamme N, Roels J, Maschalidi S, Ravichandran KS, Kasper M, van Loo G, Hoste E. Van Hove L, et al. Among authors: roels j. Autophagy. 2023 Nov;19(11):2958-2971. doi: 10.1080/15548627.2023.2247742. Epub 2023 Sep 1. Autophagy. 2023. PMID: 37615626 Free PMC article.
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state.
Van Lint S, Van Parys A, Van Den Eeckhout B, Vandamme N, Plaisance S, Verhee A, Catteeuw D, Rogge E, De Geest J, Vanderroost N, Roels J, Saeys Y, Uzé G, Kley N, Cauwels A, Tavernier J. Van Lint S, et al. Among authors: roels j. Mol Cancer. 2023 Nov 29;22(1):191. doi: 10.1186/s12943-023-01908-6. Mol Cancer. 2023. PMID: 38031106 Free PMC article.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C.
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, Bosteels C, Browaeys R, Vandamme N, Verstaen K, Roels J, Van Damme KFA, Maes B, De Leeuw E, Declercq J, Aegerter H, Seys L, Smole U, De Prijck S, Vanheerswynghels M, Claes K, Debacker V, Van Isterdael G, Backers L, Claes KBM, Bastard P, Jouanguy E, Zhang SY, Mets G, Dehoorne J, Vandekerckhove K, Schelstraete P, Willems J; MIS-C Clinicians; Stordeur P, Janssens S, Beyaert R, Saeys Y, Casanova JL, Lambrecht BN, Haerynck F, Tavernier SJ. Hoste L, et al. Among authors: roels l, roels j. J Exp Med. 2022 Feb 7;219(2):e20211381. doi: 10.1084/jem.20211381. Epub 2021 Dec 16. J Exp Med. 2022. PMID: 34914824 Free PMC article.
An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.
Houbaert D, Nikolakopoulos AP, Jacobs KA, Meçe O, Roels J, Shankar G, Agrawal M, More S, Ganne M, Rillaerts K, Boon L, Swoboda M, Nobis M, Mourao L, Bosisio F, Vandamme N, Bergers G, Scheele CLGJ, Agostinis P. Houbaert D, et al. Among authors: roels j. Cell Rep. 2024 Apr 23;43(4):114020. doi: 10.1016/j.celrep.2024.114020. Epub 2024 Mar 28. Cell Rep. 2024. PMID: 38554280 Free article.
S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice.
Gruel R, Bijnens B, Van Den Daele J, Thys S, Willems R, Wuyts D, Van Dam D, Verstraelen P, Verboven R, Roels J, Vandamme N, Mancuso R, Pita-Almenar JD, De Vos WH. Gruel R, et al. Among authors: roels j. Aging Cell. 2024 May;23(5):e14120. doi: 10.1111/acel.14120. Epub 2024 Feb 25. Aging Cell. 2024. PMID: 38403918 Free PMC article.
ThymoSpheres culture: A model to study human polyclonal unconventional T cells.
Billiet L, Jansen H, Pille M, Boehme L, Sanchez Sanchez G, De Cock L, Goetgeluk G, Pascal E, De Munter S, Deseins L, Ingels J, Michiels T, De Vos R, Zolfaghari A, Vandamme N, Roels J, Kerre T, Dmitriev RI, Taghon T, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: roels j. Eur J Immunol. 2024 Dec;54(12):e2451265. doi: 10.1002/eji.202451265. Epub 2024 Sep 9. Eur J Immunol. 2024. PMID: 39246170 Free PMC article.
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: roels j. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
100 results