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Clinical implementation of pharmacogenomics via a health system-wide research biobank: the University of Colorado experience.
Aquilante CL, Kao DP, Trinkley KE, Lin CT, Crooks KR, Hearst EC, Hess SJ, Kudron EL, Lee YM, Liko I, Lowery J, Mathias RA, Monte AA, Rafaels N, Rioth MJ, Roberts ER, Taylor MR, Williamson C, Barnes KC. Aquilante CL, et al. Among authors: barnes kc. Pharmacogenomics. 2020 Apr;21(6):375-386. doi: 10.2217/pgs-2020-0007. Epub 2020 Feb 20. Pharmacogenomics. 2020. PMID: 32077359 Free PMC article.
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.
Kessler MD, Yerges-Armstrong L, Taub MA, Shetty AC, Maloney K, Jeng LJB, Ruczinski I, Levin AM, Williams LK, Beaty TH, Mathias RA, Barnes KC; Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA); O'Connor TD. Kessler MD, et al. Among authors: barnes kc. Nat Commun. 2016 Oct 11;7:12521. doi: 10.1038/ncomms12521. Nat Commun. 2016. PMID: 27725664 Free PMC article.
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.
Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP; Understanding Society Scientific Group; Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL; Geisinger-Regeneron DiscovEHR Collaboration; Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho M… See abstract for full author list ➔ Wain LV, et al. Among authors: barnes kc. Nat Genet. 2017 Mar;49(3):416-425. doi: 10.1038/ng.3787. Epub 2017 Feb 6. Nat Genet. 2017. PMID: 28166213 Free PMC article.
The role of ST2 and ST2 genetic variants in schistosomiasis.
Long X, Daya M, Zhao J, Rafaels N, Liang H, Potee J, Campbell M, Zhang B, Araujo MI, Oliveira RR, Mathias RA, Gao L, Ruczinski I, Georas SN, Vercelli D, Beaty TH, Barnes KC, Chen X, Chen Q. Long X, et al. Among authors: barnes kc. J Allergy Clin Immunol. 2017 Nov;140(5):1416-1422.e6. doi: 10.1016/j.jaci.2016.12.969. Epub 2017 Feb 9. J Allergy Clin Immunol. 2017. PMID: 28189770 Free PMC article.
Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population.
Costa RD, Figueiredo CA, Barreto ML, Alcantara-Neves NM, Rodrigues LC, Cruz AA, Vergara C, Rafaels N, Foster C, Potee J, Campbell M, Mathias RA, Barnes KC. Costa RD, et al. Among authors: barnes kc. Ann Allergy Asthma Immunol. 2017 Apr;118(4):483-488.e1. doi: 10.1016/j.anai.2017.01.028. Epub 2017 Mar 9. Ann Allergy Asthma Immunol. 2017. PMID: 28284979 Free PMC article.
Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation.
Obeidat M, Li X, Burgess S, Zhou G, Fishbane N, Hansel NN, Bossé Y, Joubert P, Hao K, Nickle DC, van den Berge M, Timens W, Cho MH, Hobbs BD, de Jong K, Boezen M, Hung RJ, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Paré PD, Sin DD; International COPD Genetics Consortium, Lung eQTL Consortium, Lung Health Study. Obeidat M, et al. Among authors: barnes kc. Eur Respir J. 2017 Nov 30;50(5):1700657. doi: 10.1183/13993003.00657-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29191953 Free PMC article.
Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.
Blue E, Louie TL, Chong JX, Hebbring SJ, Barnes KC, Rafaels NM, Knowles MR, Gibson RL, Bamshad MJ, Emond MJ; U.S. National Heart, Lung, and Blood Institute “Grand Opportunity” Exome Sequencing Project (LungGO). Blue E, et al. Among authors: barnes kc. Ann Am Thorac Soc. 2018 Apr;15(4):440-448. doi: 10.1513/AnnalsATS.201706-451OC. Ann Am Thorac Soc. 2018. PMID: 29323929 Free PMC article.
The Emergency Medicine Specimen Bank: An Innovative Approach To Biobanking In Acute Care.
Saben JL, Shelton SK, Hopkinson AJ, Sonn BJ, Mills EB, Welham M, Westmoreland M, Zane R, Ginde AA, Bookman K, Oeth J, Chavez M, DeVivo M, Lakin A, Heldens J, Romero LB, Ames MJ, Roberts ER, Taylor M, Crooks K, Wicks SJ, Barnes KC, Monte AA. Saben JL, et al. Among authors: barnes kc. Acad Emerg Med. 2019 Jun;26(6):639-647. doi: 10.1111/acem.13620. Epub 2018 Oct 25. Acad Emerg Med. 2019. PMID: 30239069 Free PMC article.
Assembly of a pan-genome from deep sequencing of 910 humans of African descent.
Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware LB, Olopade CO, Olopade O, Oliveira RR, Ober C, Nicolae DL, Meyers DA, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker ER, Araujo MI, Herrera-Paz EF, Campbell M, Foster C, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC, Salzberg SL. Sherman RM, et al. Among authors: barnes kc. Nat Genet. 2019 Jan;51(1):30-35. doi: 10.1038/s41588-018-0273-y. Epub 2018 Nov 19. Nat Genet. 2019. PMID: 30455414 Free PMC article.
279 results