Zhang X - Search Results

1

Targeting anti-apoptotic BCL-2 family proteins for cancer treatment.

Zhang X, Liu X, Zhou D, Zheng G. Zhang X, et al. Future Med Chem. 2020 Apr;12(7):563-565. doi: 10.4155/fmc-2020-0004. Epub 2020 Feb 21. Future Med Chem. 2020. PMID: 32083493 No abstract available.

2

Muscarinic acetylcholine receptor binding affinities of pethidine analogs.

Lee NR, Zhang X, Darna M, Dwoskin LP, Zheng G. Lee NR, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5032-5. doi: 10.1016/j.bmcl.2015.10.029. Epub 2015 Oct 19. Bioorg Med Chem Lett. 2015. PMID: 26494260 Free PMC article.

3

Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one.

Bommagani S, Lee NR, Zhang X, Dwoskin LP, Zheng G. Bommagani S, et al. Among authors: zhang x. Tetrahedron Lett. 2015 Nov 18;56(46):6472-6474. doi: 10.1016/j.tetlet.2015.09.156. Tetrahedron Lett. 2015. PMID: 26663991 Free PMC article.

4

Synthesis of (2R,8' S,3' E)-δ-tocodienol, a tocoflexol family member designed to have a superior pharmacokinetic profile compared to δ-tocotrienol.

Liu X, Gujarathi S, Zhang X, Shao L, Boerma M, Compadre CM, Crooks PA, Hauer-Jensen M, Zhou D, Zheng G. Liu X, et al. Among authors: zhang x. Tetrahedron. 2016 Jul;72(27-28):4001-4006. doi: 10.1016/j.tet.2016.05.028. Epub 2016 May 12. Tetrahedron. 2016. PMID: 27773949 Free PMC article.

5

Discovery of piperlongumine as a potential novel lead for the development of senolytic agents.

Wang Y, Chang J, Liu X, Zhang X, Zhang S, Zhang X, Zhou D, Zheng G. Wang Y, et al. Among authors: zhang s, zhang x. Aging (Albany NY). 2016 Nov 19;8(11):2915-2926. doi: 10.18632/aging.101100. Aging (Albany NY). 2016. PMID: 27913811 Free PMC article.

6

Novel Linear Lipopeptide Paenipeptins with Potential for Eradicating Biofilms and Sensitizing Gram-Negative Bacteria to Rifampicin and Clarithromycin.

Moon SH, Zhang X, Zheng G, Meeker DG, Smeltzer MS, Huang E. Moon SH, et al. Among authors: zhang x. J Med Chem. 2017 Dec 14;60(23):9630-9640. doi: 10.1021/acs.jmedchem.7b01064. Epub 2017 Nov 22. J Med Chem. 2017. PMID: 29136469

7

New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells.

Hoang N, Zhang X, Zhang C, Vo V, Leng F, Saxena L, Yin F, Lu F, Zheng G, Bhowmik P, Zhang H. Hoang N, et al. Among authors: zhang c, zhang x, zhang h. Bioorg Med Chem. 2018 May 1;26(8):1523-1537. doi: 10.1016/j.bmc.2018.01.031. Epub 2018 Feb 7. Bioorg Med Chem. 2018. PMID: 29439916 Free PMC article.

8

Oxidation resistance 1 is a novel senolytic target.

Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D. Zhang X, et al. Among authors: zhang s. Aging Cell. 2018 Aug;17(4):e12780. doi: 10.1111/acel.12780. Epub 2018 May 15. Aging Cell. 2018. PMID: 29766639 Free PMC article.

9

Senolytic activity of piperlongumine analogues: Synthesis and biological evaluation.

Liu X, Wang Y, Zhang X, Gao Z, Zhang S, Shi P, Zhang X, Song L, Hendrickson H, Zhou D, Zheng G. Liu X, et al. Among authors: zhang s, zhang x. Bioorg Med Chem. 2018 Aug 7;26(14):3925-3938. doi: 10.1016/j.bmc.2018.06.013. Epub 2018 Jun 18. Bioorg Med Chem. 2018. PMID: 29925484 Free PMC article.

10

Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X_L.

Zhang X , Thummuri D , He Y , Liu X , Zhang P , Zhou D , Zheng G . Zhang X , et al. Among authors: zhang p. Chem Commun (Camb). 2019 Dec 5;55(98):14765-14768. doi: 10.1039/c9cc07217a. Chem Commun (Camb). 2019. PMID: 31754664 Free PMC article.

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