Eng C - Search Results

1

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.

Liu C, Zhao J, Lu W, Dai Y, Hockings J, Zhou Y, Nussinov R, Eng C, Cheng F. Liu C, et al. Among authors: eng c. PLoS Comput Biol. 2020 Feb 26;16(2):e1007701. doi: 10.1371/journal.pcbi.1007701. eCollection 2020 Feb. PLoS Comput Biol. 2020. PMID: 32101536 Free PMC article.

2

Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.

Cheng F, Liang H, Butte AJ, Eng C, Nussinov R. Cheng F, et al. Among authors: eng c. Pharmacol Rev. 2019 Jan;71(1):1-19. doi: 10.1124/pr.118.016253. Epub 2018 Dec 13. Pharmacol Rev. 2019. PMID: 30545954 Free PMC article. Review.

3

PTEN Mutations Trigger Resistance to Immunotherapy.

Cheng F, Eng C. Cheng F, et al. Among authors: eng c. Trends Mol Med. 2019 Jun;25(6):461-463. doi: 10.1016/j.molmed.2019.03.003. Epub 2019 Mar 27. Trends Mol Med. 2019. PMID: 30928438

4

Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer.

Smith IN, Thacker S, Seyfi M, Cheng F, Eng C. Smith IN, et al. Among authors: eng c. Am J Hum Genet. 2019 May 2;104(5):861-878. doi: 10.1016/j.ajhg.2019.03.009. Epub 2019 Apr 18. Am J Hum Genet. 2019. PMID: 31006514 Free PMC article.

5

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: eng c. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

6

A genome-wide positioning systems network algorithm for in silico drug repurposing.

Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. Cheng F, et al. Among authors: eng c. Nat Commun. 2019 Aug 2;10(1):3476. doi: 10.1038/s41467-019-10744-6. Nat Commun. 2019. PMID: 31375661 Free PMC article.

7

Pharmacogenomics: An evolving clinical tool for precision medicine.

Hockings JK, Pasternak AL, Erwin AL, Mason NT, Eng C, Hicks JK. Hockings JK, et al. Among authors: eng c. Cleve Clin J Med. 2020 Feb;87(2):91-99. doi: 10.3949/ccjm.87a.19073. Cleve Clin J Med. 2020. PMID: 32015062 Free article. Review.

8

Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors.

Akhavanfard S, Padmanabhan R, Yehia L, Cheng F, Eng C. Akhavanfard S, et al. Among authors: eng c. Nat Commun. 2020 May 5;11(1):2206. doi: 10.1038/s41467-020-16067-1. Nat Commun. 2020. PMID: 32371905 Free PMC article.

9

Pharmacogenomics for immunotherapy and immune-related cardiotoxicity.

Castrillon JA, Eng C, Cheng F. Castrillon JA, et al. Among authors: eng c. Hum Mol Genet. 2020 Oct 20;29(R2):R186-R196. doi: 10.1093/hmg/ddaa137. Hum Mol Genet. 2020. PMID: 32620943 Free PMC article. Review.

10

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis.

Hou Y, Zhao J, Martin W, Kallianpur A, Chung MK, Jehi L, Sharifi N, Erzurum S, Eng C, Cheng F. Hou Y, et al. Among authors: eng c. BMC Med. 2020 Jul 15;18(1):216. doi: 10.1186/s12916-020-01673-z. BMC Med. 2020. PMID: 32664879 Free PMC article.

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