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Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression.
Kajitani N, Iwata M, Miura A, Tsunetomi K, Yamanashi T, Matsuo R, Nishiguchi T, Fukuda S, Nagata M, Shibushita M, Yamauchi T, Pu S, Shirayama Y, Watanabe K, Kaneko K. Kajitani N, et al. Among authors: tsunetomi k. Neuropsychopharmacol Rep. 2020 Jun;40(2):157-165. doi: 10.1002/npr2.12099. Epub 2020 Mar 3. Neuropsychopharmacol Rep. 2020. PMID: 32125791 Free PMC article.
Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model.
Yamanashi T, Iwata M, Shibushita M, Tsunetomi K, Nagata M, Kajitani N, Miura A, Matsuo R, Nishiguchi T, Kato TA, Setoyama D, Shirayama Y, Watanabe K, Shinozaki G, Kaneko K. Yamanashi T, et al. Among authors: tsunetomi k. Sci Rep. 2020 Dec 10;10(1):21629. doi: 10.1038/s41598-020-78410-2. Sci Rep. 2020. PMID: 33303808 Free PMC article.
Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation.
Setoyama D, Yoshino A, Takamura M, Okada G, Iwata M, Tsunetomi K, Ohgidani M, Kuwano N, Yoshimoto J, Okamoto Y, Yamawaki S, Kanba S, Kang D, Kato TA. Setoyama D, et al. Among authors: tsunetomi k. J Affect Disord. 2021 Jan 15;279:20-30. doi: 10.1016/j.jad.2020.09.118. Epub 2020 Sep 30. J Affect Disord. 2021. PMID: 33038697