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Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma.
Hansen JD, Correa M, Nagy MA, Alexander M, Plantevin V, Grant V, Whitefield B, Huang D, Kercher T, Harris R, Narla RK, Leisten J, Tang Y, Moghaddam M, Ebinger K, Piccotti J, Havens CG, Cathers B, Carmichael J, Daniel T, Vessey R, Hamann LG, Leftheris K, Mendy D, Baculi F, LeBrun LA, Khambatta G, Lopez-Girona A. Hansen JD, et al. Among authors: alexander m. J Med Chem. 2020 Jul 9;63(13):6648-6676. doi: 10.1021/acs.jmedchem.9b01928. Epub 2020 Mar 19. J Med Chem. 2020. PMID: 32130004
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia.
Hansen JD, Correa M, Alexander M, Nagy M, Huang D, Sapienza J, Lu G, LeBrun LA, Cathers BE, Zhang W, Tang Y, Ammirante M, Narla RK, Piccotti JR, Pourdehnad M, Lopez-Girona A. Hansen JD, et al. Among authors: alexander m. J Med Chem. 2021 Feb 25;64(4):1835-1843. doi: 10.1021/acs.jmedchem.0c01489. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591756
Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation.
Norris S, Ba X, Rhodes J, Huang D, Khambatta G, Buenviaje J, Nayak S, Meiring J, Reiss S, Xu S, Shi L, Whitefield B, Alexander M, Horn EJ, Correa M, Tehrani L, Hansen JD, Papa P, Mortensen DS. Norris S, et al. Among authors: alexander m. J Med Chem. 2023 Dec 14;66(23):16388-16409. doi: 10.1021/acs.jmedchem.3c01848. Epub 2023 Nov 22. J Med Chem. 2023. PMID: 37991844
Correction to "Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation".
Norris S, Ba X, Rhodes J, Huang D, Khambatta G, Buenviaje J, Nayak S, Meiring J, Reiss S, Xu S, Shi L, Whitefield B, Alexander M, Horn EJ, Correa M, Tehrani L, Hansen JD, Papa P, Mortensen DS, Brazeau JF. Norris S, et al. Among authors: alexander m. J Med Chem. 2024 Aug 22;67(16):14692. doi: 10.1021/acs.jmedchem.4c01356. Epub 2024 Aug 13. J Med Chem. 2024. PMID: 39137243 No abstract available.
A reinvestigation of the synthesis of Hantzsch's acid: comparison of derivatives of Hantzsch's acid with a product from the reaction of 2, 4,6-trichlorophenol and hypochlorite ion in methanol.
Heasley VL, Wadley BD, Alexander MD, Anderson JD, Anderson JH, Allen RT, Hernandez ML, Ismail ML, Sigmund GA, Shellhamer DF. Heasley VL, et al. Among authors: alexander md. J Org Chem. 2000 Nov 17;65(23):8111-3. doi: 10.1021/jo0010025. J Org Chem. 2000. PMID: 11073632 No abstract available.
Androgen receptor affinity of 5'-acyl furanosteroids.
Kumar V, Ackerman JH, Alexander MD, Bell MR, Christiansen RG, Dung JS, Jaeger EP, Herrmann JL Jr, Krolski ME, McKloskey P, et al. Kumar V, et al. Among authors: alexander md. J Med Chem. 1994 Nov 25;37(24):4227-36. doi: 10.1021/jm00050a019. J Med Chem. 1994. PMID: 7990121
Exercise testing in clinical context: Reference ranges for interpreting anaerobic threshold as an outcome for congenital heart disease patients.
Hansen K, Curran T, Reynolds L, Cameron C, Pymm J, O'Neill JA, Losi R, Sherman C, Ackermans E, Yin S, Singh T, Alexander ME, Gauvreau K, Gauthier N. Hansen K, et al. Among authors: alexander me. Int J Cardiol Congenit Heart Dis. 2024 Aug 27;18:100540. doi: 10.1016/j.ijcchd.2024.100540. eCollection 2024 Dec. Int J Cardiol Congenit Heart Dis. 2024. PMID: 39713226 Free PMC article.
3,579 results