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Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
Huch M, Bonfanti P, Boj SF, Sato T, Loomans CJ, van de Wetering M, Sojoodi M, Li VS, Schuijers J, Gracanin A, Ringnalda F, Begthel H, Hamer K, Mulder J, van Es JH, de Koning E, Vries RG, Heimberg H, Clevers H. Huch M, et al. Among authors: clevers h. EMBO J. 2013 Oct 16;32(20):2708-21. doi: 10.1038/emboj.2013.204. Epub 2013 Sep 17. EMBO J. 2013. PMID: 24045232 Free PMC article.
Generation of L cells in mouse and human small intestine organoids.
Petersen N, Reimann F, Bartfeld S, Farin HF, Ringnalda FC, Vries RG, van den Brink S, Clevers H, Gribble FM, de Koning EJ. Petersen N, et al. Among authors: clevers h. Diabetes. 2014 Feb;63(2):410-20. doi: 10.2337/db13-0991. Epub 2013 Oct 15. Diabetes. 2014. PMID: 24130334 Free PMC article.
Generation of BAC transgenic epithelial organoids.
Schwank G, Andersson-Rolf A, Koo BK, Sasaki N, Clevers H. Schwank G, et al. Among authors: clevers h. PLoS One. 2013 Oct 18;8(10):e76871. doi: 10.1371/journal.pone.0076871. eCollection 2013. PLoS One. 2013. PMID: 24204693 Free PMC article.
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, Jaenisch R, Hockemeyer D. Forster R, et al. Among authors: clevers h. Stem Cell Reports. 2014 Jun 3;2(6):838-52. doi: 10.1016/j.stemcr.2014.05.001. eCollection 2014 Jun 3. Stem Cell Reports. 2014. PMID: 24936470 Free PMC article.
Sequential cancer mutations in cultured human intestinal stem cells.
Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: clevers h. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068
Expanding intestinal stem cells in culture.
Heo I, Clevers H. Heo I, et al. Among authors: clevers h. Cell Res. 2015 Sep;25(9):995-6. doi: 10.1038/cr.2015.83. Epub 2015 Jul 14. Cell Res. 2015. PMID: 26169607 Free PMC article.
835 results