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Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter Š, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, Kellam P, Zavala F, Ward AB, Wilson IA. Oyen D, et al. Among authors: kellam p. PLoS Pathog. 2020 Mar 9;16(3):e1008373. doi: 10.1371/journal.ppat.1008373. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32150583 Free PMC article.
Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane.
Smith SE, Busse DC, Binter S, Weston S, Diaz Soria C, Laksono BM, Clare S, Van Nieuwkoop S, Van den Hoogen BG, Clement M, Marsden M, Humphreys IR, Marsh M, de Swart RL, Wash RS, Tregoning JS, Kellam P. Smith SE, et al. Among authors: kellam p. J Virol. 2019 Mar 5;93(6):e02003-18. doi: 10.1128/JVI.02003-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567988 Free PMC article.
IFITM3 restricts the morbidity and mortality associated with influenza.
Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, Chin CR, Feeley EM, Sims JS, Adams DJ, Wise HM, Kane L, Goulding D, Digard P, Anttila V, Baillie JK, Walsh TS, Hume DA, Palotie A, Xue Y, Colonna V, Tyler-Smith C, Dunning J, Gordon SB; GenISIS Investigators; MOSAIC Investigators; Smyth RL, Openshaw PJ, Dougan G, Brass AL, Kellam P. Everitt AR, et al. Among authors: kellam p. Nature. 2012 Mar 25;484(7395):519-23. doi: 10.1038/nature10921. Nature. 2012. PMID: 22446628 Free PMC article.
Whole genome analysis of local Kenyan and global sequences unravels the epidemiological and molecular evolutionary dynamics of RSV genotype ON1 strains.
Otieno JR, Kamau EM, Oketch JW, Ngoi JM, Gichuki AM, Binter Š, Otieno GP, Ngama M, Agoti CN, Cane PA, Kellam P, Cotten M, Lemey P, Nokes DJ. Otieno JR, et al. Among authors: kellam p. Virus Evol. 2018 Sep 24;4(2):vey027. doi: 10.1093/ve/vey027. eCollection 2018 Jul. Virus Evol. 2018. PMID: 30271623 Free PMC article.
Genome-wide evolutionary dynamics of influenza B viruses on a global scale.
Langat P, Raghwani J, Dudas G, Bowden TA, Edwards S, Gall A, Bedford T, Rambaut A, Daniels RS, Russell CA, Pybus OG, McCauley J, Kellam P, Watson SJ. Langat P, et al. Among authors: kellam p. PLoS Pathog. 2017 Dec 28;13(12):e1006749. doi: 10.1371/journal.ppat.1006749. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29284042 Free PMC article.
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii.
Baker S, Krishna A, Higham S, Naydenova P, O'Leary S, Scott JB, Harcourt K, Forrest S, Goulding D, Thi Nguyen TN, Toan ND, Alekseeva E, Zhou Q, Andreozzi I, Sobotic B, Craig H, Wong V, Forrest-Owen N, Sanchez DM, Pearce C, Roberts L, Watson S, Clare S, Torok ME, Dougan G, Kellam P, Tregoning JS, Reece ST. Baker S, et al. Among authors: kellam p. Nat Commun. 2024 Sep 12;15(1):7979. doi: 10.1038/s41467-024-52357-8. Nat Commun. 2024. PMID: 39266557 Free PMC article.
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study.
Hastie KM, Li H, Bedinger D, Schendel SL, Dennison SM, Li K, Rayaprolu V, Yu X, Mann C, Zandonatti M, Diaz Avalos R, Zyla D, Buck T, Hui S, Shaffer K, Hariharan C, Yin J, Olmedillas E, Enriquez A, Parekh D, Abraha M, Feeney E, Horn GQ; CoVIC-DB team1; Aldon Y, Ali H, Aracic S, Cobb RR, Federman RS, Fernandez JM, Glanville J, Green R, Grigoryan G, Lujan Hernandez AG, Ho DD, Huang KA, Ingraham J, Jiang W, Kellam P, Kim C, Kim M, Kim HM, Kong C, Krebs SJ, Lan F, Lang G, Lee S, Leung CL, Liu J, Lu Y, MacCamy A, McGuire AT, Palser AL, Rabbitts TH, Rikhtegaran Tehrani Z, Sajadi MM, Sanders RW, Sato AK, Schweizer L, Seo J, Shen B, Snitselaar JL, Stamatatos L, Tan Y, Tomic MT, van Gils MJ, Youssef S, Yu J, Yuan TZ, Zhang Q, Peters B, Tomaras GD, Germann T, Saphire EO. Hastie KM, et al. Among authors: kellam p. Science. 2021 Oct 22;374(6566):472-478. doi: 10.1126/science.abh2315. Epub 2021 Sep 23. Science. 2021. PMID: 34554826 Free PMC article.
IFITM proteins-cellular inhibitors of viral entry.
Smith S, Weston S, Kellam P, Marsh M. Smith S, et al. Among authors: kellam p. Curr Opin Virol. 2014 Feb;4:71-7. doi: 10.1016/j.coviro.2013.11.004. Epub 2014 Jan 28. Curr Opin Virol. 2014. PMID: 24480526 Free PMC article. Review.
Erratum: Whole genome analysis of local Kenyan and global sequences unravels the epidemiological and molecular evolutionary dynamics of RSV genotype ON1 strains.
Otieno JR, Kamau EM, Oketch JW, Ngoi JM, Gichuki AM, Binter Š, Otieno GP, Ngama M, Agoti CN, Cane PA, Kellam P, Cotten M, Lemey P, Nokes DJ. Otieno JR, et al. Among authors: kellam p. Virus Evol. 2018 Nov 16;4(2):vey036. doi: 10.1093/ve/vey036. eCollection 2018 Jul. Virus Evol. 2018. PMID: 30464856 Free PMC article.
319 results