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A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Liu Y, Jurczak MJ, Lear TB, Lin B, Larsen MB, Kennerdell JR, Chen Y, Huckestein BR, Nguyen MK, Tuncer F, Jiang Y, Monga SP, O'Donnell CP, Finkel T, Chen BB, Mallampalli RK. Liu Y, et al. Among authors: chen bb, chen y. Nat Chem Biol. 2021 Mar;17(3):298-306. doi: 10.1038/s41589-020-00723-0. Epub 2021 Jan 25. Nat Chem Biol. 2021. PMID: 33495648 Free PMC article.
The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity.
Tong Y, Lear TB, Evankovich J, Chen Y, Londino JD, Myerburg MM, Zhang Y, Popescu ID, McDyer JF, McVerry BJ, Lockwood KC, Jurczak MJ, Liu Y, Chen BB. Tong Y, et al. Among authors: chen bb, chen y. JCI Insight. 2020 Feb 13;5(3):e133652. doi: 10.1172/jci.insight.133652. JCI Insight. 2020. PMID: 31990690 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35560756
Fibronectin-EDA accumulates via reduced ubiquitination downstream of Toll-like receptor 9 activation in SSc-ILD fibroblasts.
Tuncer F, Bulik M, Villandre J, Lear T, Chen Y, Tuncer B, Kass DJ, Valenzi E, Morse C, Sembrat J 2nd, Lafyatis R, Chen B, Evankovich J. Tuncer F, et al. Among authors: chen b, chen y. Am J Physiol Lung Cell Mol Physiol. 2022 Oct 1;323(4):L484-L494. doi: 10.1152/ajplung.00019.2022. Epub 2022 Aug 23. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35997276 Free PMC article.
A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry.
Chen Y, Lear TB, Evankovich JW, Larsen MB, Lin B, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Lockwood KC, Liu J, Myerburg MM, McDyer JF, Liu Y, Finkel T, Chen BB. Chen Y, et al. Among authors: chen bb. Res Sq [Preprint]. 2020 Aug 14:rs.3.rs-48659. doi: 10.21203/rs.3.rs-48659/v1. Res Sq. 2020. Update in: Nat Commun. 2021 Jun 23;12(1):3907. doi: 10.1038/s41467-021-24156-y PMID: 32818215 Free PMC article. Updated. Preprint.
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