Carvalho LAR - Search Results

1

3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling.

Carvalho LAR, Almeida VT, Brito JA, Lum KM, Oliveira TF, Guedes RC, Gonçalves LM, Lucas SD, Cravatt BF, Archer M, Moreira R. Carvalho LAR, et al. ACS Chem Biol. 2020 Apr 17;15(4):878-883. doi: 10.1021/acschembio.0c00090. Epub 2020 Mar 20. ACS Chem Biol. 2020. PMID: 32176480

2

Application of a vibration measuring technique to evaluate the dynamic stiffness of porcine periodontal ligament.

Carvalho L, Moreira RA, Simões JA. Carvalho L, et al. Technol Health Care. 2006;14(4-5):457-65. Technol Health Care. 2006. PMID: 17065766

3

Optimization of O3-acyl kojic acid derivatives as potent and selective human neutrophil elastase inhibitors.

Lucas SD, Gonçalves LM, Carvalho LA, Correia HF, Da Costa EM, Guedes RA, Moreira R, Guedes RC. Lucas SD, et al. J Med Chem. 2013 Dec 12;56(23):9802-6. doi: 10.1021/jm4011725. Epub 2013 Nov 20. J Med Chem. 2013. PMID: 24224573

4

Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.

Ruivo EF, Gonçalves LM, Carvalho LA, Guedes RC, Hofbauer S, Brito JA, Archer M, Moreira R, Lucas SD. Ruivo EF, et al. ChemMedChem. 2016 Sep 20;11(18):2037-42. doi: 10.1002/cmdc.201600258. Epub 2016 Jul 28. ChemMedChem. 2016. PMID: 27465595

5

Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation.

Falcão AS, Carvalho LA, Lidónio G, Vaz AR, Lucas SD, Moreira R, Brites D. Falcão AS, et al. ACS Chem Neurosci. 2017 Jan 18;8(1):89-99. doi: 10.1021/acschemneuro.6b00250. Epub 2016 Nov 15. ACS Chem Neurosci. 2017. PMID: 27797173

6

Phenotypic Effects of Wild-Type and Mutant SOD1 Expression in N9 Murine Microglia at Steady State, Inflammatory and Immunomodulatory Conditions.

Vaz AR, Pinto S, Ezequiel C, Cunha C, Carvalho LA, Moreira R, Brites D. Vaz AR, et al. Front Cell Neurosci. 2019 Apr 9;13:109. doi: 10.3389/fncel.2019.00109. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31024256 Free PMC article.

7

Recovery of Depleted miR-146a in ALS Cortical Astrocytes Reverts Cell Aberrancies and Prevents Paracrine Pathogenicity on Microglia and Motor Neurons.

Barbosa M, Gomes C, Sequeira C, Gonçalves-Ribeiro J, Pina CC, Carvalho LA, Moreira R, Vaz SH, Vaz AR, Brites D. Barbosa M, et al. Front Cell Dev Biol. 2021 Apr 23;9:634355. doi: 10.3389/fcell.2021.634355. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33968923 Free PMC article.

8

Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.

Carvalho LAR, Ross B, Fehr L, Bolgi O, Wöhrle S, Lum KM, Podlesainski D, Vieira AC, Kiefersauer R, Félix R, Rodrigues T, Lucas SD, Groß O, Geiss-Friedlander R, Cravatt BF, Huber R, Kaiser M, Moreira R. Carvalho LAR, et al. Angew Chem Int Ed Engl. 2022 Nov 21;61(47):e202210498. doi: 10.1002/anie.202210498. Epub 2022 Oct 28. Angew Chem Int Ed Engl. 2022. PMID: 36089535 Free PMC article.

9

4-Oxo-β-Lactams as Novel Inhibitors for Rhomboid Proteases.

Yang J, Carvalho LAR, Ji S, Chen S, Moreira R, Verhelst SHL. Yang J, et al. Among authors: carvalho lar. Chembiochem. 2023 Nov 2;24(21):e202300418. doi: 10.1002/cbic.202300418. Epub 2023 Sep 15. Chembiochem. 2023. PMID: 37671979

10

The Impact of Activity-Based Protein Profiling in Malaria Drug Discovery.

Carvalho LAR, Bernardes GJL. Carvalho LAR, et al. ChemMedChem. 2022 Jul 19;17(14):e202200174. doi: 10.1002/cmdc.202200174. Epub 2022 May 19. ChemMedChem. 2022. PMID: 35506504 Free PMC article. Review.

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