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A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.
Niphakis MJ, Lum KM, Cognetta AB 3rd, Correia BE, Ichu TA, Olucha J, Brown SJ, Kundu S, Piscitelli F, Rosen H, Cravatt BF. Niphakis MJ, et al. Among authors: lum km. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045. Cell. 2015. PMID: 26091042 Free PMC article.
Proteome-wide covalent ligand discovery in native biological systems.
Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF. Backus KM, et al. Among authors: lum km. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15. Nature. 2016. PMID: 27309814 Free PMC article.
Chemical Proteomic Profiling of Human Methyltransferases.
Horning BD, Suciu RM, Ghadiri DA, Ulanovskaya OA, Matthews ML, Lum KM, Backus KM, Brown SJ, Rosen H, Cravatt BF. Horning BD, et al. Among authors: lum km. J Am Chem Soc. 2016 Oct 12;138(40):13335-13343. doi: 10.1021/jacs.6b07830. Epub 2016 Sep 30. J Am Chem Soc. 2016. PMID: 27689866 Free PMC article.
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
Chen AL, Lum KM, Lara-Gonzalez P, Ogasawara D, Cognetta AB 3rd, To A, Parsons WH, Simon GM, Desai A, Petrascheck M, Bar-Peled L, Cravatt BF. Chen AL, et al. Among authors: lum km. Nat Chem Biol. 2019 May;15(5):453-462. doi: 10.1038/s41589-019-0243-4. Epub 2019 Mar 25. Nat Chem Biol. 2019. PMID: 30911178 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: lum km. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
22 results