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Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure.
Arnold K, Xu Y, Sparkenbaugh EM, Li M, Han X, Zhang X, Xia K, Piegore M, Zhang F, Zhang X, Henderson M, Pagadala V, Su G, Tan L, Park PW, Stravitz RT, Key NS, Linhardt RJ, Pawlinski R, Xu D, Liu J. Arnold K, et al. Among authors: sparkenbaugh em. Sci Transl Med. 2020 Mar 18;12(535):eaav8075. doi: 10.1126/scitranslmed.aav8075. Sci Transl Med. 2020. PMID: 32188725 Free PMC article.
Protease activated receptor-2 contributes to heart failure.
Antoniak S, Sparkenbaugh EM, Tencati M, Rojas M, Mackman N, Pawlinski R. Antoniak S, et al. Among authors: sparkenbaugh em. PLoS One. 2013 Nov 27;8(11):e81733. doi: 10.1371/journal.pone.0081733. eCollection 2013. PLoS One. 2013. PMID: 24312345 Free PMC article.
Homogeneous low-molecular-weight heparins with reversible anticoagulant activity.
Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J. Xu Y, et al. Among authors: sparkenbaugh em. Nat Chem Biol. 2014 Apr;10(4):248-50. doi: 10.1038/nchembio.1459. Epub 2014 Feb 23. Nat Chem Biol. 2014. PMID: 24561662 Free PMC article.
Excess of heme induces tissue factor-dependent activation of coagulation in mice.
Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R. Sparkenbaugh EM, et al. Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728. Epub 2015 Jan 16. Haematologica. 2015. PMID: 25596265 Free PMC article.
41 results