Ortiz MA - Search Results

1

Discovery of cyclic guanidine-linked sulfonamides as inhibitors of LMTK3 kinase.

Ortiz MA, Michaels H, Molina B, Toenjes S, Davis J, Marconi GD, Hecht D, Gustafson JL, Piedrafita FJ, Nefzi A. Ortiz MA, et al. Bioorg Med Chem Lett. 2020 May 1;30(9):127108. doi: 10.1016/j.bmcl.2020.127108. Epub 2020 Mar 17. Bioorg Med Chem Lett. 2020. PMID: 32192797

2

Thyroid hormone receptor homodimers can function as ligand-sensitive repressors.

Piedrafita FJ, Bendik I, Ortiz MA, Pfahl M. Piedrafita FJ, et al. Among authors: ortiz ma. Mol Endocrinol. 1995 May;9(5):563-78. doi: 10.1210/mend.9.5.7565804. Mol Endocrinol. 1995. PMID: 7565804

3

Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.

Piedrafita FJ, Ortiz MA, Pfahl M. Piedrafita FJ, et al. Among authors: ortiz ma. Mol Endocrinol. 1995 Nov;9(11):1533-48. doi: 10.1210/mend.9.11.8584031. Mol Endocrinol. 1995. PMID: 8584031

4

TOR: a new orphan receptor expressed in the thymus that can modulate retinoid and thyroid hormone signals.

Ortiz MA, Piedrafita FJ, Pfahl M, Maki R. Ortiz MA, et al. Mol Endocrinol. 1995 Dec;9(12):1679-91. doi: 10.1210/mend.9.12.8614404. Mol Endocrinol. 1995. PMID: 8614404

5

Ortiz MA, Lopez-Hernandez FJ, Bayon Y, Pfahl M, Piedrafita FJ. Ortiz MA, et al. Cancer Res. 2001 Dec 1;61(23):8504-12. Cancer Res. 2001. PMID: 11731435

6

Retinoids in combination therapies for the treatment of cancer: mechanisms and perspectives.

Ortiz MA, Bayon Y, Lopez-Hernandez FJ, Piedrafita FJ. Ortiz MA, et al. Drug Resist Updat. 2002 Jul-Aug;5(3-4):162-75. doi: 10.1016/s1368-7646(02)00050-x. Drug Resist Updat. 2002. PMID: 12237083 Review.

7

Inhibition of IkappaB kinase by a new class of retinoid-related anticancer agents that induce apoptosis.

Bayon Y, Ortiz MA, Lopez-Hernandez FJ, Gao F, Karin M, Pfahl M, Piedrafita FJ. Bayon Y, et al. Among authors: ortiz ma. Mol Cell Biol. 2003 Feb;23(3):1061-74. doi: 10.1128/MCB.23.3.1061-1074.2003. Mol Cell Biol. 2003. PMID: 12529410 Free PMC article.

8

Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway.

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Among authors: ortiz ma. Mol Cancer Ther. 2003 Mar;2(3):255-63. Mol Cancer Ther. 2003. PMID: 12657720

9

Reduced concentrations of serum enhance the antiproliferative activity of retinoid-related molecules and accelerate the onset of apoptosis.

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Among authors: ortiz ma. Biochem Pharmacol. 2003 Jun 15;65(12):2021-30. doi: 10.1016/s0006-2952(03)00195-3. Biochem Pharmacol. 2003. PMID: 12787882

10

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Among authors: ortiz ma. Cell Death Differ. 2004 Feb;11(2):154-64. doi: 10.1038/sj.cdd.4401329. Cell Death Differ. 2004. PMID: 14576769

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