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The taming of PARP1 and its impact on NAD+ metabolism.
Hurtado-Bagès S, Knobloch G, Ladurner AG, Buschbeck M. Hurtado-Bagès S, et al. Among authors: buschbeck m. Mol Metab. 2020 Aug;38:100950. doi: 10.1016/j.molmet.2020.01.014. Epub 2020 Feb 12. Mol Metab. 2020. PMID: 32199820 Free PMC article. Review.
Macro domains as metabolite sensors on chromatin.
Posavec M, Timinszky G, Buschbeck M. Posavec M, et al. Among authors: buschbeck m. Cell Mol Life Sci. 2013 May;70(9):1509-24. doi: 10.1007/s00018-013-1294-4. Epub 2013 Mar 3. Cell Mol Life Sci. 2013. PMID: 23455074 Free PMC article. Review.
MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.
Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M. Posavec Marjanović M, et al. Among authors: buschbeck m. Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991266 Free PMC article.
MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez-Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG. Kozlowski M, et al. Among authors: buschbeck m. EMBO Rep. 2018 Oct;19(10):e44445. doi: 10.15252/embr.201744445. Epub 2018 Sep 3. EMBO Rep. 2018. PMID: 30177554 Free PMC article.
Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype.
Vieira-Silva TS, Monteiro-Reis S, Barros-Silva D, Ramalho-Carvalho J, Graça I, Carneiro I, Martins AT, Oliveira J, Antunes L, Hurtado-Bagès S, Buschbeck M, Henrique R, Jerónimo C. Vieira-Silva TS, et al. Among authors: buschbeck m. Cancer Cell Int. 2019 Apr 29;19:112. doi: 10.1186/s12935-019-0835-9. eCollection 2019. Cancer Cell Int. 2019. PMID: 31164793 Free PMC article.
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1.
Simonet NG, Thackray JK, Vazquez BN, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, Hurtado-Bagès S, Sabidó E, Buschbeck M, Tischfield J, De La Torre C, Esteller M, Braun T, Olivella M, Serrano L, Vaquero A. Simonet NG, et al. Among authors: buschbeck m. Sci Adv. 2020 Jul 24;6(30):eaaz2590. doi: 10.1126/sciadv.aaz2590. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832656 Free PMC article.
Evolution of a histone variant involved in compartmental regulation of NAD metabolism.
Guberovic I, Hurtado-Bagès S, Rivera-Casas C, Knobloch G, Malinverni R, Valero V, Leger MM, García J, Basquin J, Gómez de Cedrón M, Frigolé-Vivas M, Cheema MS, Pérez A, Ausió J, Ramírez de Molina A, Salvatella X, Ruiz-Trillo I, Eirin-Lopez JM, Ladurner AG, Buschbeck M. Guberovic I, et al. Among authors: buschbeck m. Nat Struct Mol Biol. 2021 Dec;28(12):1009-1019. doi: 10.1038/s41594-021-00692-5. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887560 Free article.
79 results