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Page 1
Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.
Wakabayashi Y, Telu S, Dick RM, Fujita M, Ooms M, Morse CL, Liow JS, Hong JS, Gladding RL, Manly LS, Zoghbi SS, Mo X, D'Amato EC, Sindac JA, Nugent RA, Marron BE, Gurney ME, Innis RB, Pike VW. Wakabayashi Y, et al. Among authors: ooms m. ACS Chem Neurosci. 2020 May 6;11(9):1311-1323. doi: 10.1021/acschemneuro.0c00077. Epub 2020 Apr 8. ACS Chem Neurosci. 2020. PMID: 32212718 Free PMC article.
[11C](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice.
Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M. Ooms M, et al. J Cereb Blood Flow Metab. 2019 Jul;39(7):1306-1313. doi: 10.1177/0271678X18758997. Epub 2018 Feb 12. J Cereb Blood Flow Metab. 2019. PMID: 29430995 Free PMC article.
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.
Wakabayashi Y, Stenkrona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Santamaria JAM, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, Schmidt CJ, Doran SD, Mannes A, Zanotti-Fregonara P, Ooms M, Morse CL, Zoghbi SS, Halldin C, Pike VW, Innis RB. Wakabayashi Y, et al. Among authors: ooms m. J Nucl Med. 2022 Dec;63(12):1919-1924. doi: 10.2967/jnumed.122.263838. Epub 2022 Jun 30. J Nucl Med. 2022. PMID: 35772961 Free PMC article.
Preclinical evaluation of [(18)F]JNJ42259152 as a PET tracer for PDE10A.
Celen S, Koole M, Ooms M, De Angelis M, Sannen I, Cornelis J, Alcazar J, Schmidt M, Verbruggen A, Langlois X, Van Laere K, Andrés JI, Bormans G. Celen S, et al. Among authors: ooms m. Neuroimage. 2013 Nov 15;82:13-22. doi: 10.1016/j.neuroimage.2013.04.123. Epub 2013 May 9. Neuroimage. 2013. PMID: 23664955
Retention of [(18)F]fluoride on reversed phase HPLC columns.
Ory D, Van den Brande J, de Groot T, Serdons K, Bex M, Declercq L, Cleeren F, Ooms M, Van Laere K, Verbruggen A, Bormans G. Ory D, et al. Among authors: ooms m. J Pharm Biomed Anal. 2015;111:209-14. doi: 10.1016/j.jpba.2015.04.009. Epub 2015 Apr 9. J Pharm Biomed Anal. 2015. PMID: 25898315
235 results