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Page 1
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers.
Li BT, Michelini F, Misale S, Cocco E, Baldino L, Cai Y, Shifman S, Tu HY, Myers ML, Xu C, Mattar M, Khodos I, Little M, Qeriqi B, Weitsman G, Wilhem CJ, Lalani AS, Diala I, Freedman RA, Lin NU, Solit DB, Berger MF, Barber PR, Ng T, Offin M, Isbell JM, Jones DR, Yu HA, Thyparambil S, Liao WL, Bhalkikar A, Cecchi F, Hyman DM, Lewis JS, Buonocore DJ, Ho AL, Makker V, Reis-Filho JS, Razavi P, Arcila ME, Kris MG, Poirier JT, Shen R, Tsurutani J, Ulaner GA, de Stanchina E, Rosen N, Rudin CM, Scaltriti M. Li BT, et al. Among authors: barber pr. Cancer Discov. 2020 May;10(5):674-687. doi: 10.1158/2159-8290.CD-20-0215. Epub 2020 Mar 25. Cancer Discov. 2020. PMID: 32213539 Free PMC article.
How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology.
Fruhwirth GO, Fernandes LP, Weitsman G, Patel G, Kelleher M, Lawler K, Brock A, Poland SP, Matthews DR, Kéri G, Barber PR, Vojnovic B, Ameer-Beg SM, Coolen AC, Fraternali F, Ng T. Fruhwirth GO, et al. Among authors: barber pr. Chemphyschem. 2011 Feb 25;12(3):442-61. doi: 10.1002/cphc.201000866. Epub 2011 Feb 15. Chemphyschem. 2011. PMID: 21328516 Review.
A multi-functional imaging approach to high-content protein interaction screening.
Matthews DR, Fruhwirth GO, Weitsman G, Carlin LM, Ofo E, Keppler M, Barber PR, Tullis ID, Vojnovic B, Ng T, Ameer-Beg SM. Matthews DR, et al. Among authors: barber pr. PLoS One. 2012;7(4):e33231. doi: 10.1371/journal.pone.0033231. Epub 2012 Apr 10. PLoS One. 2012. PMID: 22506000 Free PMC article.
Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer.
Tao JJ, Castel P, Radosevic-Robin N, Elkabets M, Auricchio N, Aceto N, Weitsman G, Barber P, Vojnovic B, Ellis H, Morse N, Viola-Villegas NT, Bosch A, Juric D, Hazra S, Singh S, Kim P, Bergamaschi A, Maheswaran S, Ng T, Penault-Llorca F, Lewis JS, Carey LA, Perou CM, Baselga J, Scaltriti M. Tao JJ, et al. Sci Signal. 2014 Mar 25;7(318):ra29. doi: 10.1126/scisignal.2005125. Sci Signal. 2014. PMID: 24667376 Free PMC article.
Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.
Coban O, Zanetti-Dominguez LC, Matthews DR, Rolfe DJ, Weitsman G, Barber PR, Barbeau J, Devauges V, Kampmeier F, Winn M, Vojnovic B, Parker PJ, Lidke KA, Lidke DS, Ameer-Beg SM, Martin-Fernandez ML, Ng T. Coban O, et al. Among authors: barber pr. Biophys J. 2015 Mar 10;108(5):1013-26. doi: 10.1016/j.bpj.2015.01.005. Biophys J. 2015. PMID: 25762314 Free PMC article.
HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status.
Weitsman G, Barber PR, Nguyen LK, Lawler K, Patel G, Woodman N, Kelleher MT, Pinder SE, Rowley M, Ellis PA, Purushotham AD, Coolen AC, Kholodenko BN, Vojnovic B, Gillett C, Ng T. Weitsman G, et al. Among authors: barber pr. Oncotarget. 2016 Aug 9;7(32):51012-51026. doi: 10.18632/oncotarget.9963. Oncotarget. 2016. PMID: 27618787 Free PMC article.
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Bosch-Vilaró A, Jacobs B, Pomella V, Abbasi Asbagh L, Kirkland R, Michel J, Singh S, Liu X, Kim P, Weitsman G, Barber PR, Vojnovic B, Ng T, Tejpar S. Bosch-Vilaró A, et al. Among authors: barber pr. Oncotarget. 2017 Jan 17;8(3):4277-4288. doi: 10.18632/oncotarget.13834. Oncotarget. 2017. PMID: 28032592 Free PMC article.
Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.
Weitsman G, Mitchell NJ, Evans R, Cheung A, Kalber TL, Bofinger R, Fruhwirth GO, Keppler M, Wright ZVF, Barber PR, Gordon P, de Koning T, Wulaningsih W, Sander K, Vojnovic B, Ameer-Beg S, Lythgoe M, Arnold JN, Årstad E, Festy F, Hailes HC, Tabor AB, Ng T. Weitsman G, et al. Among authors: barber pr. Oncogene. 2017 Jun 22;36(25):3618-3628. doi: 10.1038/onc.2016.522. Epub 2017 Feb 6. Oncogene. 2017. PMID: 28166195 Free PMC article.
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.
Claus J, Patel G, Autore F, Colomba A, Weitsman G, Soliman TN, Roberts S, Zanetti-Domingues LC, Hirsch M, Collu F, George R, Ortiz-Zapater E, Barber PR, Vojnovic B, Yarden Y, Martin-Fernandez ML, Cameron A, Fraternali F, Ng T, Parker PJ. Claus J, et al. Among authors: barber pr. Elife. 2018 May 1;7:e32271. doi: 10.7554/eLife.32271. Elife. 2018. PMID: 29712619 Free PMC article.
68 results